Toxic epidermal necrolysis (TEN) is a rare, life-threatening drug-induced skin disease with mortality rate of approximately 30%. The clinical hallmark TEN marked detachment caused by extensive keratinocyte cell death associated mucosal involvement. We have two cases presented within 3 months and successfully treated cyclosporine.

Background: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis comprise a spectrum of severe hypersensitivity skin reactions. is the least on mucosal erosions, with being most severe. Syndrome/Toxic disease keratinocytes therefore any squamous cell epithelium at risk. This includes cornea, conjunctiva, oral mucosa, esophagus, urethra, anal canal. reaction typically drug-induced has very po...

AMA Knosala E, Wąsik G. Toxic epidermal necrolysis in a patient with lupus erythematosus. Dermatology Review/Przegląd Dermatologiczny. 2023;110(2):176-179. doi:10.5114/dr.2023.127830. APA Knosala, E., & Wąsik, (2023). Dermatologiczny, 110(2), 176-179. https://doi.org/10.5114/dr.2023.127830 Chicago Emilia, and Grażyna Wąsik. 2023. "Toxic erythematosus". Dermatologiczny 110 (2): Harvard pp.176-17...