objective: safety of lippia citriodora, as a herbal remedy, in pregnancy has not yet been evaluated. this study aimed to identify the effect of l. citriodora aqueous extract on pregnancy outcome in mice. materials and methods: timed-pregnant mice received doses of 0.5 g/kg/day l. citriodora aqueous extract or the vehicle control during organogenesis, intraperitoneally. maternal body weights wer...

objective(s) portulaca oleracea l. is a herbaceous weed from portulacaceae family. it can be found in many parts of the world. modern pharmacological studies have demonstrated that p. oleracea have antioxidant effects. the protective effect of aqueous and ethanolic extract of p. oleracea against cisplatin-induced renal toxicity was studied in rats. materials and methods single intraperitoneal i...

background: nicotiana tobacco contains large amounts of alkaloid nicotine. tobacco plant is used for smoking and causes many health problems since it is high in nicotine which is one of the widely-recognized toxic compounds with serious side effects for different body organs. reducing nicotine content of this plant is a way to reduce its health hazards in cigarette smokers. utilizing the new me...

objective(s): anti-epileptic drugs (aeds) have the potential to affect fetal development throughout pregnancy. considering the broad therapeutic indications of pregabalin (pgb), its potential teratogenic effects and the levels of homocysteine have been studied.   materials and methods: timed-pregnant mice received one of three doses of pgb (20, 40 or 80 mg/kg/day) or the vehicle control during ...

b a ckground: we aimed to extract the ingredients from leaves of gossypium hirsutum (bt cotton) using different solvents and evaluate for potential use to control different larval stages of mosquito species, aedes aegypti and anoph eles stephensi . m e t hods: qualitative and quantitative estimation of ingredients from go. hirsutum (bt) plant extract was carried out and their inhibitory action ...

abstract       background and objectives: antibiotic resistance in bacteria has actuated researchers toward evaluating many new antibacterial compounds of which are the thiazoles. in this research the inhibitory effects of novel thiazole derivatives were unraveled on staphylococcus aureus, streptococcus agalactiae, pseudomonas aeruginosa and klebsiella pneumoniae and oxothiazole liver toxicity ...

conclusions the current study findings indicated that echinacea purpurea extract played an important role in the protection against den toxicity in rats. results den induced hepatotoxicity and nephrotoxicity in all the treated animals by elevated serum alt, ast, alp and bun, creatinin and total and direct bilirubin levels. ast, bun and total and direct bilirubin significantly decreased in den +...

background: the entrance of toxic compounds into wastewater treatment plants (wwtps) can induce disorder in their biological units. therefore, it is necessary to determine the sources of toxic wastewaters. in this study, the toxicity of the wastewater of 3 metal plating industries was assessed using sequencing batch reactor (sbr) bacteria. methods: to obtain the 1-1000 ml/l concentrations, the ...

Machine learning models are commonly used to detect toxicity in online conversations. These trained on datasets annotated by human raters. We explore how raters' self-described identities impact they annotate comments. first define the concept of Specialized Rater Pools: rater pools formed based identities, rather than at random. three such for this study - specialized raters from U.S. who iden...