نتایج جستجو برای: toxicological reference

تعداد نتایج: 280237  

Journal: :Revista brasileira de enfermagem 2011
Juliana Lourenço de Araújo Veras Cintia Regina Tornisiello Katz

This study aimed to assess cases of self-inflicted poisoning among adolescents reported by the Toxicological Care Center of a reference hospital in Recife-PE, Brazil. The data were collected between March and May 2010 from hospital charts and structured interviews with the participants and parents/guardians. Among the 25 cases of attempted suicide registered in the period, 21 were female adoles...

2011
L.A. Dykman N.G. Khlebtsov

Functionalized gold nanoparticles with controlled geometrical and optical properties are the subject of intensive studies and biomedical applications, including genomics, biosensorics, immunoassays, clinical chemistry, laser phototherapy of cancer cells and tumors, the targeted delivery of drugs, DNA and antigens, optical bioimaging and the monitoring of cells and tissues with the use of state-...

Journal: :Pharmacogenomics 2002
Markus Ringnér Carsten Peterson Javed Khan

Pharmacogenomics is the application of genomic technologies to drug discovery and development, as well as for the elucidation of the mechanisms of drug action on cells and organisms. DNA microarrays measure genome-wide gene expression patterns and are an important tool for pharmacogenomic applications, such as the identification of molecular targets for drugs, toxicological studies and molecula...

2004
M. A. AKANMU E. O. IWALEWA A. A. ELUJOBA K. A. ADELUSOLA

The aqueous extract of the pods of Cassia fistula Linn (Leguminosae Caesalpinoideae), cultivated in Ile-Ife, Nigeria were investigated for pharmacological and toxicological properties. The in-vitro effect of Cassia fistula infusion on isolated guinea-pig ileum was examined. The acute and sub-chronic toxicity of the infusion of C. fistula and Cassia acutifolia Del. Pod(Senokot tablet) as the ref...

Journal: :ALTEX 2015
Mounir Bouhifd Melvin E Andersen Christina Baghdikian Kim Boekelheide Kevin M Crofton Albert J Fornace Andre Kleensang Henghong Li Carolina Livi Alexandra Maertens Patrick D McMullen Michael Rosenberg Russell Thomas Marguerite Vantangoli James D Yager Liang Zhao Thomas Hartung

The Human Toxome Project, funded as an NIH Transformative Research grant 2011-2016, is focused on developing the concepts and the means for deducing, validating and sharing molecular pathways of toxicity (PoT). Using the test case of estrogenic endocrine disruption, the responses of MCF-7 human breast cancer cells are being phenotyped by transcriptomics and mass-spectroscopy-based metabolomics....

2002

Barium and Compounds Substance File (IRIS Ba File). The influential information contained in this file fails to comply with the OMB " Guidelines for Ensuring and Maximizing the Quality, Objectivity, Utility, and Integrity of Information Disseminated by Federal Agencies ". The information disseminated in EPA's IRIS Barium and Compounds file directly contradicts the information published by EPA i...

Journal: :Cancer research 1963
S S STERNBERG F S PHILIPS A P CRONIN J E SODERGREN P M VIDAL

Calvacin is a potent, antitumor mucoprotein which is cumulative in effect and which causes a prolonged intoxication characterized by anorexia and extreme weight loss. It induces a wide spectrum of lesions in experimental mammals. The more promi nent include hepatic necrosis, biliary obstruction, renal tubular necrosis, fibrinoid degeneration, myofibrillar necrosis in cardiac and skeletal muscle...

2013

 Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzo-p-furans (“dioxins”) is a term used to refer to a group of 210 compounds with similar chemical structures  Most of these compounds pose no health hazard at the levels commonly found but 17 of them are of more toxicological concern  The most toxic dioxin is 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and most of the available data ...

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