When immunocompetent people become infected with the parasite Toxoplasma gondii, the disease is generally asymptomatic. However, transplacental transmission of T. gondii may lead to severe congenital infection including in utero abortion, foetal death, or neurological or ocular damage of the foetus. France has had a national programme to prevent congenital toxoplasmosis since 1978. However, alt...

Background Congenital toxoplasmosis is an important cause of spontaneous abortion worldwide. However, there is limited information on detection and genotypic characterization of T. gondii in women with recurrent spontaneous abortion (RSA). The aim of this study is molecular detection and genotypic characterization of T. gondii in formalin-fixed, paraffin-embedded fetoplacental tissues (FFPTs) o...

Pregnancy is a highly regulated process, requiring strict control of the immune system in order to prevent rejection of the semiallogenic foetus. One aspect of pregnancy immunology that has been of great interest is the influence of female sex and pregnancy associated hormones, such as progesterone and oestrogen, on cells of the immune system. This review evaluates studies investigating the abi...

background: the diagnosis of toxoplasmosis is most critical in pregnant women who acquire infection during gestation and also in fetuses and newborns who are congenitally infected. this study described the performance of molecular and confirmatory serologic testing for toxoplasma infection in the tissues of human spontaneous aborted fetuses and their mothers' blood. materials and methods: ...

Ocular toxoplasmosis (OT) is a major cause of posterior uveitis worldwide but its incidence and prevalence are difficult to establish precisely. In 1993, a survey in a French Hospital Service of Ophthalmology showed that OT was seen in less than 1 per thousand outpatients [1]. In a study performed in Germany, toxoplasmosis accounted for 4.2 % of all cases of uveitis at a referral centre [2]. Ar...

For more than three decades, mother-child care programs have included screening for Toxoplasma infections in pregnancy by means of laboratory tests from blood samples in some countries (esp. Austria and France) [1-3]. Recently, despite much international research, the efficiency of this approach in preventing toxoplasmosis in the fetus has been questioned, more on the ground of inconclusive dat...

Between 1 January, 1995 and 6 September, 1995, there have been 110 acute Toxoplasma gondii infections identified among individuals in the Greater Victoria area. Of these, 42 infected women and 11 newborns have been identified through a pregnancy-related screening program, which began on 24 April, 1995. Fifty-seven infections have been identified in non-pregnant individuals. This outbreak of tox...

BACKGROUND Toxoplasmosis is one of the common worldwide parasitic zoonosis due to Toxoplasma gondii (T. gondii). Toxoplasmosis during pregnancy can result in fetal and neonatal death or various congenital defects. The aim of this study was to assess the seroprevalence and risk factors of T. gondii infection in pregnant women following antenatal care (ANC) services at Bobo Dioulasso. METHODS A...