نتایج جستجو برای: transfused patients
تعداد نتایج: 2085994 فیلتر نتایج به سال:
Allogeneic blood transfusions have been reported to induce immunomodulation in recipients of blood products. While the mechanism(s) of this immunomodulatory effect is unknown, it has been suggested that this effect of allogeneic blood transfusions could adversely affect patients with a malignant disorder. These concerns have been supported by a number of nonrandomized, mainly retrospective, cli...
This exploratory study assessed apoptosis in peripheral blood leucocytes (PBL) from β-thalassaemia patients receiving chronic transfusions and chelation therapy (deferasirox or deferoxamine) at baseline, 1, 6, and 12 months. At baseline, thalassaemic PBLs presented 50% greater levels of Bax (BAX), 75% higher caspase-3/7, 48% higher caspase-8 and 88% higher caspase-9 activities and 428% more nuc...
The characteristics and natural history of alloimmunization to HLA were studied in five patients with Hunter's syndrome receiving long term transfusions of leukocytes collected from human leukocyte antigen (HLA) matched donors. Patients were not given any other blood component transfusions. All patients became alloimmunized at an average interval of eight months following an average of 15 trans...
background: to determine factors that predicts icu and ward stay during hospitalization for coronary artery surgery. methods: data were collected retrospectively from 200 patients. icu and ward stay time was divided into two groups and compared by x 2 and t test and variables with a p value of less than 0.1 were included in logistic regression model. specificity and sensitivity of tests were ex...
In a group of stable, nonthrombocytopenic leukemia patients awaiting bone marrow transplantation, results of paired allogeneic radiolabeled platelet kinetic measurements were correlated with the results of several different platelet and lymphocytotoxic antibody tests to determine which parameters could be used to identify patients who were alloimmunized to platelets. Seven patients with acute l...
OBJECTIVE To explore the hypothesis that blood transfusion contributes to an immunosuppressed phenotype in severely injured patients. BACKGROUND Despite trauma patients using disproportionately large quantities of blood and blood products, the immunomodulatory effects of blood transfusion in this group are inadequately described. METHODS A total of 112 ventilated polytrauma patients were re...
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