نتایج جستجو برای: transgenic mouse

تعداد نتایج: 324509  

Journal: :Photoacoustics 2021

The abnormal deposition of fibrillar beta-amyloid (A?) deposits in the brain is one major histopathological hallmarks Alzheimer’s disease (AD). Here, we characterized curcumin-derivative CRANAD-2 for multi-spectral optoacoustic tomography and fluorescence imaging A? arcA? mouse model AD cerebral amyloidosis. showed a specific quantitative detection fibrils vitro, even complex mixtures, it capab...

Journal: :Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1992
G Stamp V Fantl R Poulsom S Jamieson R Smith G Peters C Dickson

We have developed transgenic mice in which expression of the mouse int-2/Fgf-3 gene is regulated by a single long terminal repeat from mouse mammary tumor virus. Such mice contain and transmit a replica of the activated int-2/Fgf-3 allele present in a spontaneous mammary tumor from a BR6 mouse. Although free of infectious mouse mammary tumor virus and with a different genetic background, the tr...

Journal: :American journal of physiology. Heart and circulatory physiology 2006
Jason A Wall Jing Wei Mimi Ly Peter Belmont Joshua J Martindale Diem Tran Jun Sun Wenqiong J Chen Wen Yu Paul Oeller Steve Briggs Asa B Gustafsson M R Sayen Roberta A Gottlieb Christopher C Glembotski

Ischemia-reperfusion (I/R) has critical consequences in the heart. Recent studies on the functions of I/R-activated kinases, such as p38 mitogen-activated protein kinase (MAPK), showed that I/R injury is reduced in the hearts of transgenic mice that overexpress the p38 MAPK activator MAPK kinase 6 (MKK6). This protection may be fostered by changes in the levels of many proteins not currently kn...

Journal: :European Journal of Echocardiography 2006

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