نتایج جستجو برای: transglutaminases
تعداد نتایج: 1752 فیلتر نتایج به سال:
Mammalian transglutaminases (TGs) catalyze calcium-dependent irreversible posttranslational modifications of proteins and their enzymatic activities contribute to the pathogenesis several human neurodegenerative diseases. Although different are found in many tissues, TG6 isoform is mostly expressed CNS. The present study was embarked on/undertaken investigate expression, distribution activity H...
In five lines of cultured human squamous carcinoma cells, transglutaminase activity and envelope competence were highly sensitive to retinoic acid and calcium levels in the growth medium. In cells grown in low calcium medium, these measures of keratinocyte differentiation were reduced. Retinoic acid suppressed envelope competence but total transglutaminase activity was markedly reduced, slightl...
OBJECTIVE To investigate the expression of transglutaminases (TGs) in the ocular surface, the eyelid margin and associated glands and to determine effect of muscarinic agents on TGs in scleral fibroblasts (SF). MATERIALS AND METHODS Primary SFs cultured from mouse and human sclera were treated with atropine and carbachol for 5 days. Lysed cell RNA was used for real-time PCR, protein was used ...
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