BACKGROUND Observations of abnormalities in the diastolic components of intracellular Ca2+ transients in failing human left ventricular myocardium have raised the possibility that reductions in the level or function of sarcoplasmic reticulum proteins involved in Ca2+ transport contribute to the pathophysiology of dilated cardiomyopathy in humans. Functional assays, however, have revealed no dif...

We report the electrical and optical properties of two-component blends of electron and hole transporting materials in single and bilayer structures for organic light emitting diode ~OLED! applications. The materials considered were a blue-emitting bipolar transporting polyfluorene, poly~9,9-di-n-hexylfluorene! ~DHF!, and a hole-transporting material, poly-@4-nhexyltriphenylamine# ~HTPA!. We co...

The two presumed calmodulin antagonists calmidazolium and compound 48/80 were compared for their effects on several calmodulin-dependent and calmodulin-independent enzyme systems. Compound 48/80 and calmidazolium were found to be about equipotent in antagonizing the calmodulin-dependent fraction of brain phosphodiesterase and erythrocyte Ca2+-transporting ATPase. Compound 48/80 combines high po...

Although drunk driving in the United States is a violent crime, driving impaired with a child in the vehicle is not typically acknowledged as child endangerment. The U.S. Department of Transportation and advocacy groups are struggling to improve public awareness of this issue, and recently, child-endangerment laws are receiving more attention. For this study, we examined the characteristics of ...

This study presented the effects of carrier-transporting layer (CTL) on electroluminescence (EL) performance a blue phosphorescent organic light-emitting diodes (PHOLEDs) with electron transporting host based three kinds electron-transporting layers (ETLs) including 3-(4-biphenyl-yl)-4-phenyl-5-(4-tert-butylphenyl)-1,2,4-triazole (TAZ), diphenyl-bis[4-(pyridin-3-yl)phenyl]silane (DPPS) and 1,3,...

Bovine hypothalamus contains a nonpeptidic substance that inhibits purified Na+/K(+)-transporting ATPase [ATP phosphohydrolase (Na+/K(+)-transporting), EC 3.6.1.37] reversibly with high affinity by a mechanism similar to, but not identical to, that of the cardiac glycosides. It possesses some of the characteristics ascribed to a putative endogenous "digitalis-like" compound that has been implic...

OBJECTIVE To evaluate the screening measures that would have been required to assess all travellers at risk of transporting A(H1N1)pdm09 out of Mexico by air at the start of the 2009 pandemic. METHODS Data from flight itineraries for travellers who flew from Mexico were used to estimate the number of international airports where health screening measures would have been needed, and the number...