The extent of muscle pathology in sedentary adult mdx mice is very low and treadmill exercise is often used to increase myofibre necrosis; however, the early events in dystrophic muscle and blood in response to treadmill exercise (leading to myofibre necrosis) are unknown. This study describes in detail two standardised protocols for the treadmill exercise of mdx mice and profiles changes in mo...

The purpose of this study was to investigate the possible effects of a treadmill training program on regeneration in young (3-month-old) and mature (13-month-old) rats with sciatic nerve crush using functional, electrophysiological, and morphometric analyses. When compared to both the young and mature untrained injury groups, those groups that underwent a treadmill training showed improved sens...

Methods: This was a hospital-based, randomized controlled trial with a blinded assessor. Twenty four chronic stroke patients who were more than six months post-stroke participated in this study. They were randomly allocated to 1 of 2 groups: Real-time Auditory stimulation Feedback (RAF) group (n= 12) and treadmill group (n=12). Patients in the RAF group received three 30-minute sessions of trea...

BACKGROUND Left ventricular wall motion abnormalities (LVWMA) observed during cardiovascular magnetic resonance (CMR) pharmacologic stress testing can be used to determine cardiac prognosis, but currently, information regarding the prognostic utility of upright maximal treadmill induced LVWMA is unknown. Our objective was to determine the prognostic utility of upright maximal treadmill exercise...

—The purpose of this study was to assess whether a treadmill mile is an acceptable FitnessGram® Test substitute for the traditional one-mile run for middle school boys and girls. Peak heart rate and perceived physical exertion of the participants were also measured to assess students’ eff ort. 48 boys and 40 girls participated, with approximately 85% classifi ed as Hispanic. Boys’ mean time for...

INTRODUCTION Peripheral arterial disease (PAD) is defined by atherosclerotic plaque buildup and subsequent blockages along the arterial walls of the extremities[1]. The narrowing of the arteries leads to reduced blood flow to the leg musculature upon exertion clinically resulting in complaints of leg pain. This pain, known as claudication, stops once muscular exertion ceases and metabolic deman...

INTRODUCTION Increased adrenergic tone might be an additional trigger of orthostatic stress of vasovagal syncope (VVS). Exercise before standing might provide increased sensitivity compared to standing using a sublingual nitroglycerines protocol during tilt table testing. The aim of this study was to evaluate the diagnostic value of treadmill testing before standing with nitroglycerin administr...

This study evaluated whether an exercise treadmill test could predict restenosis in 289 patients 6 months after a successful emergency angioplasty of the infarct-related artery for acute myocardial infarction. After excluding those with interim interventions (64), medical events (36), or medical contraindications to follow-up testing (25), both a treadmill test and a cardiac catheterization wer...

(AD). Although physical exercise and AD have received attention in the scientific literature, the mechanism through which treadmill exercise may impact the brain insulin signaling of AD has not been elucidated. This study aimed to evaluate the neuroprotective effects of treadmill exercise on apoptotic factors (Bcl-2/Bax ratio, caspase-3), HSP70, COX-2, BDNF and PI3-K/Akt signaling pathway in th...

To compare the hemodynamic and gas exchange responses of ramp treadmill and cycle ergometer tests with standard exercise protocols used clinically, 10 patients with chronic heart failure, 10 with coronary artery disease who were asymptomatic during exercise, 11 with coronary artery disease who were limited by angina during exercise and 10 age-matched normal subjects performed maximal exercise u...