The results of high speed air drill lung biopsy during 38 months in Addis Ababa is reported. Even though the diagnostic yield was only 49%, trephine lung biopsy has a place in the investigation of diffuse and accessible localised lesions of the lung. It has proved to be a relatively safe and simple procedure. Nineteen male and 20 female patients were studied and in addition eight postmortem spe...

Myeloproliferative neoplasm-unclassifiable (MPN-U) presents an MPN-type phenotype that fails to meet diagnostic criteria for other MPN variants. Variability in the clinicopathological phenotypes many challenges. Amongst a registry cohort of 1512 patients with MPN, 82 MPN-U were included, median (range) age 49·7 (13–79) years. Albeit heterogeneous, common presentation features included raised la...

Lymphomas are malignant neoplasms of lymphoid cells present usually as solid mass in the organs body. They have a tendency to metastasize different parts body and bone marrow is one most frequent sites. infiltrate particular hence form various patterns infiltration. Each lymphoma has its characteristic or more Recognition such pattern can often help diagnosis lymphoma. This was prospective desc...

Bone marrow necrosis (BMN) is regarded as an infrequent and rare pathological finding in the aspirates trephine biopsies. It a histological which may be associated with infections, sickle cell disease, leukemia other diseases. Its postmortem prevalence ranges from 0.3% to 2.2%., BMN might also seen prior to, or following diagnosis of neoplasia, ordering subsequent treatments chemotherapy radiot...

Early phases of polycythemia vera, essential thrombocythemia, and primary myelofibrosis (PMF) can be difficult to distinguish by morphologic studies alone because they share many morphologic characteristics. Histologic criteria according to the 2008 World Health Organization (WHO) classification are part of the myeloproliferative neoplasia (MPN) diagnosis. Our aim was to assess the reproducibil...