Calcium phosphatCalcium phosphate cement (CPC) is a material used to fill bone defects. Its advantages include being able irregularly shaped spaces, its similarity tissue, and ease of biodegradation. However, insufficient durability unpredictable rate resorption limit CPC use. Objective. Study the dynamics morphological changes in rat femurs after implanting two types based on metastable αʹ‒tri...

Articular cartilage defects are a major clinical burden worldwide. Current methods to repair bone defects include bone autografts, allografts and external fixation. In recent years, the repair of bone defects by tissue engineering has emerged as a promising approach. The present study aimed to assess a novel method using a biological reactor with platelet-rich plasma to construct tissue-enginee...

Cytotherapy for bone regeneration has not been widely used clinically. A new method based on enriched bone-marrow-derived mesenchymal stem cells (MSCs) combined with porous beta-tricalcium phosphate (beta-TCP) was used for posterior spinal fusion in 41 patients. The aim of the present study was to assess the clinical feasibility of peri-operative bone marrow stem cell enrichment and their combi...

The ability of apatite to form on the surface of biomaterials in simulated body fluid (SBF) has been widely used to predict the bone-bonding ability of bioceramic and bioceramic/polymer composites in vivo. Porous β-tricalcium phosphate/poly(L-lactic acid) (β-TCP/PLLA) composite scaffold was synthesized by new method. The ability of inducing calcium phosphate (Ca-P) formation was compared in sta...

Abstract Objectives Rehabilitation of edentulous ridges to promote the insertion dental implants has been key indicator for retaining osseous structures since tooth extraction. Recombinant Bone Morphogenetic Protein-2(rhBMP-2) is exploited bone augmentation due its osteoinductive capacity. The objective study determine effectiveness induction implant placement by rhBMP-2 delivered on beta-trica...

Abstract Background Artificial bone graft substitutes (ABGS) for curettage of tumors are becoming increasingly popular. The aim this retrospective analysis was to determine the efficacy ABGS Cerasorb (Curasan-AG, Kleinostheim, Germany), a beta-tricalcium phosphate (beta-TCP), concerning resorption profile, healing, and remodeling after surgery evaluate potential complications. Methods Forty-thr...

Calcium phosphates (CaPs) have broad applications in biomedicine, with the most used phases being hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP) due to their similarity natural bone. There are several methods for obtaining CaPs. However, Pechini method attracts much attention its advantages: homogeneous molecular mixing, nanocrystalline particles, low processing temperature, generating...

Calcium phosphate cement (CPC) that is based on α-tricalcium phosphate (α-TCP) is considered desirable for bone tissue engineering because of its relatively rapid degradation properties. However, such cement is relatively weak, restricting its use to areas of low mechanical stress. Wollastonite fibers (WF) have been used to improve the mechanical strength of biomaterials. However, the biologica...

Calcium phosphate ceramics are widely used as bone substitutes since they are biocompatible and bioactive. Given that their chemical composition is close to natural bone, calcium phosphate ceramics are promising bone substitute materials in orthopaedics, maxillofacial surgery and dentistry. Hydroxyapatite (HA) and tricalcium phosphate (TCP) are the most commonly used calcium phosphates, because...

Magnesium hydrogen phosphate (MHP, MgHPO4) recovered from swine manure was prepared as an alternative phosphorus (P) source. Conventional P additives, monocalcium phosphate (MCP), dicalcium phosphate (DCP), and tricalcium phosphate (TCP) were compared with the MHP in terms of growth and P availability by juvenile carp Cyprinus carpio. A basal diet as a negative control was prepared using practi...