A unique lipopeptide antimycotic, termed cryptocandin, is described from Cryptosporiopsis cf. quercina, an endophytic fungus. Cryptocandin, with a molecular mass of 1079 Da, contains equimolar amounts of 3,4-dihydroxyhomotyrosine, 4-hydroxyproline, threonine, glutamine, 3-hydroxy-4-hydroxymethylproline, 4,5-dihydroxyornithine and palmitic acid. Cryptocandin is chemically related to well-known a...

We report here the first case of neonatal tinea faciei caused by Trichophyton tonsurans in mainland China. The mother of the infant had tinea corpris and tinea capitis while the father had tinea incongnito. The infections in the parents were mycologically confirmed to be due to Trichophyton tonsurans. Ttinea faciei in the infant was cured after two-week topical use of amorolfine cream. The moth...

Tinea pedis (athlete’s foot) is a common fungal infection of the feet with the major causative organisms being Trichophyton rubrum, Trichophyton mentagrophytes and Epidermophyton floccosum1. It occurs worldwide, with a greater frequency and severity during the warmer months of the year. The condition is most prevalent in adult men, especially in the presence of excessive perspiration and occlus...

We reported herein the synthesis, antifungal activity, docking and in silico ADME prediction studies of four novel series of sulfones 6a-f, 8a-c, 10a-f and 12a-c. All the newly synthesized sulfones were tested against four strains of Candida (including fluconazole-resistant Candida), two strains of Aspergillus, two dermatophytic fungi (Trichophytons mentagrophyte and Microsporum canis) and Sync...

in recent times increasing occurrence of dermatophytosis, especially among the school children in eastern india was evidenced along with increased tendency of keeping companion animals such as dogs and cats. this study was undertaken to detect the occurrence of dermatophytes with antifungal susceptibility among the companion animals. a total of 1501 healthy companion animals comprising 1209 dog...

Background: Dermatophytes are the most common fungal agents causing superficial skin infections in worldwide. Species identification of these fungi is important for therapeutic and epidemiological apects. The purpose of this study was to determine the epidemiology of dermatophytosis in patients referring to medical mycology laboratory of Razi hospital in Tehran, during 2014. Materials and Meth...

Background and Aims: Amino acids have different effects on the growth of some dermatophytes. Some may increase whereas others maydecrease their growth. The concentration of some amino acids is also an important factor for their effects. Materials and Methods: To investigate the effects of L-amino acids on the growth of six species of dermatophytes including Epidermophyton floccosum, Microspor...

Dermatophytosis is an infection of tissue containing horny substances, such as the stratum corneum in epidermis, hair, and nails. The caused by fungus genus Trichophyton, one which Trichophyton mentagrophytes. Aloe vera leaves contain saponins flavonoids are known to have antimicrobial effect inhibit fungi. Antifungal products can be processed various dosage forms, spray. This study aims determ...