Multi-target strategies are directed toward targets that are unrelated (or distantly related) and can create opportunities to address different pathologies. The antidermatophytic activities of nine natural skin lighteners: α-bisabolol, kojic acid, β-arbutin, azelaic acid, hydroquinone, nicotinamide, glycine, glutathione and ascorbyl tetraisopalmitate, were evaluated, in comparison with the know...

During the period January 1999 to July 2002 a total de 164 cases of Tinea capitis were diagnosed by mycological examination in Instituto de Patologia Tropical e Saúde Pública of the Universidade Federal de Goiás. Of the 164 patients 94 (57.3%) were males, with an age of 3 months to 13 years. Laboratory studies were performed by direct examination with 20% KOH and cultivated on Mycobiotic agar m...

24 A rapid two step DNA extraction method and a multiplex PCR for the detection of 25 dermatophytes in general and Trichophyton (T.) rubrum specifically were developed and 26 evaluated on DNA extracted from pure cultures and from clinically diseased nails. DNA 27 from the following dermatophytes were used: Epidermophyton floccosum, Microsporum 28 (M.) audouinii, M. canis, M. gypseum, M. nanum, ...

Prevalence of dermatophytosis, with respect to age and sex and dermatophyte species, in Jaen was investigated during a period of three years (1996-1999). The prevalence of dermatophytosis over three years was 4.48 cases / 1000 inhabitants. The isolated species were: Microsporum canis (48.6%), Trichophyton mentagrophytes (27.1%), Epidermophyton floccosum (10%), Trichophyton rubrum (8.6%), Tricho...

A case of a tinea capitis caused by Trichophyton schoenleinii is presented. It involves a 6-year old Tunisian boy that had presented with diffuse scaling of the scalp misdiagnosed as psoriasis and was treated unsuccessfully with keratolytic shampoos for two years. Tinea favosa due to Trichophyton schoenleinii was confirmed by mycological examination. He was successfully treated with griseofulvi...

Anja Bornkessel*, Mirjana Ziemer, Siegrid Yu, Christina Hipler and Peter Elsner Department of Dermatology and Allergology, Friedrich-Schiller-University, Erfurter Str. 35, D-07743 Jena, Germany, and Department of Dermatology, University of California, San Francisco, CA, USA. *E-mail: [email protected] [The first two authors contributed equally to the writing of this paper.] Accept...