Trigger finger at wrist is a rare condition. Symptoms include finger triggering, snapping or catching at the wrist level. Carpal tunnel syndrome and median nerve compression neuropathy are almost always associated. We reported one case which was caused by degenerative changes of the flexor tendon sheath and carpal tunnel syndrome.

We present MultiPoint, a set of perspective-based remote pointing techniques that allows users to perform bimanual and multi-finger remote manipulation of graphical objects on large displays. We conducted two empirical studies that compared remote pointing techniques performed using fingers and laser pointers, in single and multi-finger pointing interactions. We explored three types of manual s...

Central precocious puberty (CPP) is attributed to the disorder of some trigger factors those can activate the hypothalamic-pituitary-gonadal axis controlled by GnRH neurons. Many recent studies reveal one of those trigger factors, Makorin ring finger protein 3 (Mkrn3), whose loss-of-function mutations are implicated in CPP. Although Mkrn3 contained zinc Ring finger domain is considered as a put...

The conditioning model of binge eating states that cues such as the sight, smell and taste of binge food prepare the binger's body for the intake of large amounts of food. The bodily preparations are supposed to be felt as an almost irresistible urge to binge. In the present study, the validity of the model was tested. Clinical binge eaters (bulimia nervosa patients) and healthy control partici...

I thank Drs. Quintner and Cohen for their interest in my editorial [1] about the study by Albrect et al. [2]. Drs. Quintner and Cohen have raised several concerns about my discussion of the implications of that study, especially of the concept that peripheral nociception by myofascial trigger points initiates central sensitization. They object to the idea that peripheral nerve sensitization is ...

The highly processive transcription by multi-subunit RNA polymerases (RNAP) can be interrupted by misincorporation or backtracking events that may stall transcription or lead to erroneous transcripts. Backtracked/misincorporated complexes can be resolved via hydrolysis of the transcript. Here, we show that, in response to misincorporation and/or backtracking, the catalytic domain of RNAP active...

Emotion regulation is a crucial skill in adulthood; its acquisition represents one of the key developmental tasks in early childhood. Difficulties with adaptive emotion regulation increase the risk of psychopathology in childhood and adulthood. This is, for instance, shown by a relation between emotion regulation and aggressive behavior in childhood age, indicating emotion dysregulation as an i...