The copulas of random vectors with standard uniform univariate margins truncated from the right are considered and a general formula for such right-truncated conditional is derived. This analytical that can be inverted analytically as functions each single argument. case Archimedean related copulas. resulting not only tractable but also characterized tilted copulas, one main contributions this ...

Spinocerebellar ataxia type 3 (SCA3), known as Machado-Joseph disease, is an autosomal dominant disease caused by an abnormal expansion of polyglutamine in ATXN3 gene, leading to neurodegeneration in SCA3 patients. Similar to other neurodegenerative diseases, the dysfunction of mitochondria is observed to cause neuronal death in SCA3 patients. Based on previous studies, proteolytic cleavage of ...

One candidate for a mesoderm-inducing factor in early amphibian development is activin, a member of the TGF beta family. Overexpression of a truncated form of an activin receptor Type IIB abolishes activin responsiveness and mesoderm formation in vivo. The Xenopus Type IIA activin receptor XSTK9 differs from the Type IIB receptor by 43 and 25% in extracellular and intracellular domains respecti...

The tyrosine kinase receptor trkB is thought to mediate the biological actions of brain-derived neurotrophic factor. This receptor is expressed by a large variety of neurons during development. Truncated trkB molecules lacking the tyrosine kinase domain have also been described, but their functions remain elusive. In order to gain insight into their role, we studied the pattern of expression an...

We give a definition of full level structure on group schemes the form $$G\times G$$ , where G is finite flat commutative scheme rank p over $${\mathbb {Z}}_p$$ -scheme S or, more generally, truncated p-divisible height 1. show that there no natural notion stack all schemes.

The natural preconditioner defined by local potentials is effective in the truncated Newton method for minimizing large scale biomolecular potential energy functions. This paper extends its definition, and proposes an algorithm for generating the sparse pattern of the preconditioner from the primary structure of a molecular system with N atoms. It shows that the implementation of the new compre...

This study analyses the technical efficiency of Saudi banks using a two-stage DEA-data envelopment analysis approach. In the first stage, we use a bootstrapped DEA–VRS model to identify the efficiency scores, and in the second stage, we use a bootstrapped truncated regression model to identify the covariates that explain technical efficiency. Policy implications are derived. 2010 Elsevier Ltd. ...

Human stem cell factor initiates a diverse array of cellular responses, including hematopoiesis, cell proliferation, differentiation, migration and survival. To explore the relationship between its structure and function, we produced recombinant soluble human stem cell factor1-165 (wild type) and human stem cell factor1-141 (C-terminal truncated) in a yeast expression system and compared their ...

Recombinant truncated forms of Pseudomonas exotoxin A that lack the cell binding domain of Pseudomonas exotoxin A were coupled to an F(ab') fragment of a monoclonal antibody HB21 directed against the human transferrin receptor. One of these was NlysPE40. The other, NlysPE38QQRi has two amino groups on residues near the NH2-terminus and has no amino groups near the COOH-terminus. The proteins we...