Signal transduction through epidermal growth factor receptors (EGFRs) is essential for the growth and development of multicellular organisms. A genetic screen for regulators of EGFR signaling has led to the identification of Sprouty, a cell autonomous inhibitor of EGF signaling that is transcriptionally induced by the pathway. However, the molecular mechanisms by which Sprouty exerts its antago...

It is proposed that if the spirogram is truncated for moment analysis, this should be done with respect to volume and not time. Errors are incurred when the moments of one spirogram are compared with those of another. These errors are maximal with no truncation and are reduced by truncation. A method is described for deriving sequential truncated moments of the forced expiratory spirogram. The ...

We derive the decomposition of the anisotropic Gaussian in a one-dimensional (1-D) Gauss filter in the x-direction followed by a 1-D filter in a nonorthogonal direction phi. So also the anisotropic Gaussian can be decomposed by dimension. This appears to be extremely efficient from a computing perspective. An implementation scheme for normal convolution and for recursive filtering is proposed. ...

Schwarz methods use a decomposition of the computational domain into subdomains and need to impose boundary conditions on subdomain boundaries. In truncation one restricts unbounded bounded must also put both fields there are vast bodies literature research is very active ongoing. It turns out be fruitful think in as onto subdomains. Seminal precursors this fundamental idea papers by Hagstrom, ...

Caspase-mediated truncation of tau is associated with aggregation. We examined the impact of manipulation of caspase activity on intracellular aggregation of a mutant form of tau (3PO) that forms spontaneous aggregates. Treatment with the caspase inhibitor Z-VAD-fmk reduced both N and C-terminal tau truncation but did not significantly reduce aggregation. Treatment with staurosporine, which act...

An Adaptive Block Truncation Coding Scheme and Its Data-Driven Parallel Implementation