Giant cell tumor of spine (GCTS) is one common benign tumor with high recurrence rate after surgery. The finding of novel index for predicting recurrence is thus of critical importance. Matrix metalloproteinase (MMP) can work as prognostic indexes for various tumors, and is shown to be negatively related with RECK gene expression. This study thus examined the levels of MMP-2, MMP-9 and RECK in ...

The aim of the present study was to identify the most useful markers for predicting recurrence of keratocystic odontogenic tumors (KCOTs). A total of 65 tumor samples from 63 patients diagnosed with typical parakeratinized cysts and KCOTs between 1992 and 2014 were retrospectively studied. Clinical and histopathological data and treatment modality were reviewed. In addition, the expression prof...

calcifying aponeurotic fibroma (caf) is a rare, benign fibroblastic tumor that typically occurs in the palms of the hands and soles of the feet, in children and adolescents. due to its infiltrative nature, this tumor can mimic malignancy on preoperative magnetic resonance imaging (mri) and has a predilection for local recurrence. there are very few reports in the literature that describe featur...

PURPOSE The study was aimed to evaluate the prognostic or predictive value of serum exosomal microRNAs (miRNAs) for tumor recurrence and response to adjuvant therapy in stage II and stage III colon cancer. RESULTS 145 differentially expressed mature miRNAs were identified (P<0.05) and 10 top hits were carried forward in validation test. MiR-4772-3p was significantly under-expressed in 27 pati...

PURPOSE Hepatic resection is a standard method of treatment for colorectal liver metastases (CRLM). However, the pathologic factors of metastatic lesions that affect tumor recurrence are less well defined in CRLM. The aim of this study was to evaluate the risk factors for recurrence of CRLM, focusing on histopathologic factors of metastatic lesions of the liver. METHODS From January 2003 to D...

BACKGROUND We conducted this retrospective study to analyze the relationship between the distance of the proximal resection margin (PRM) and the pattern of recurrence in patients with gastric cancer who underwent curative gastrectomy. METHODS In our series, there were 774 patients who underwent curative gastrectomy for gastric adenocarcinoma. Thus, we classified our clinical series of patient...

BACKGROUND Bevacizumab, a humanized monoclonal antibody against vascular endothelial growth factor, may have activity in recurrent malignant gliomas. At recurrence some patients appear to develop nonenhancing infiltrating disease rather than enhancing tumor. METHODS We retrospectively reviewed 55 consecutive patients with recurrent malignant gliomas who received bevacizumab and chemotherapy t...

BACKGROUND/AIMS Extended cholecystectomy is generally recommended for patients with T2 gallbladder cancer. However, few studies have assessed the extent of resection relative to T2 gallbladder tumor location. This study analyzed the effects of surgical methods and tumor location on survival outcomes and tumor recurrence in patients with T2 gallbladder cancer. METHODS Clinicopathological chara...

Objective: To analyze factors related to the prognosis of primary extra-gastrointestinal stromal tumors (EGISTs). Methods: The pathological and clinical data of 42 patients with primary EGISTs was collected and retrospectively analyzed. The patients were hospitalized from January 2004 to December 2013 and received complete surgical resection in Ruijin Hospital. The follow-up of postoperative pa...