Postural stability becomes compromised with advancing age, but the neural mechanisms contributing to instability have not been fully explicated. Accordingly, this quantitative physiological and MRI study of sex differences across the adult age range examined the association between components of postural control and the integrity of brain structure and function under different conditions of sen...

BACKGROUND The metabolic syndrome is a prevalent condition that carries with it an increased risk of type 2 diabetes mellitus, cardiovascular disease (CVD), and mortality. OBJECTIVE To determine the relationship between cardiorespiratory fitness (CRF) and mortality in healthy men and in those with the metabolic syndrome. METHODS The sample included 19 223 men, aged 20 to 83 years, who recei...

Chlamydia trachomatis (Ct) serological studies in populations could help monitor changes in lifetime cumulative risk of infection. We developed a double-antigen sandwich ELISA based on the Ct-specific Pgp3 antigen, then tested blind stored sera from over 800 participants in a New Zealand birth cohort from Dunedin at ages 26, 32 and 38. The double-antigen sandwich ELISA was more sensitive than o...

objectives: the onset of multiple sclerosis in the majority of the cases occurs as a clinically isolated syndrome (cis). we sought to assess serum levels of 25-hydroxyvitamin d (25-ohd) in cis patients and healthy controls. methods: in this cross-sectional study 40 patients (36 women and 4 men) with cis manifesting as a single isolated optic neuritis and 40 age- and sex-matched healthy controls...

In order to establish reference equations for prediction of the total distance walked during six minutes (6MWD) for healthy adults, we administered the standardized 6-min walk test to 117 healthy men and 173 healthy women, aged 40 to 80 yr. Oxygen saturation (SaO2), pulse rate, and the degree of dyspnea (Borg scale) were determined before and at the end of the walk. The median distance walked w...

The purpose of the study is to examine healthy eating habits of the population of Serbia through three dimensions: knowledge, problems, and feelings as well as to determine whether there are any differences between genders and among different age-groups. The research instrument was an Eating Habits Questionnaire (EHQ) which consisted of 35 items. There were 382 respondents involved in the study...

BACKGROUND Identifying factors influencing phenotypic heterogeneity in Parkinson's Disease is crucial for understanding variability in disease severity and progression. Age and gender are two most basic epidemiological characteristics, yet their effect on expression of PD symptoms is not fully defined. We aimed to delineate effects of age and gender on the phenotype in an incident cohort of PD ...

The relative contributions of aging and coronary heart disease to the impairment of functional capacity were assessed in 117 coronary patients, 117 age-matched healthy middle-aged men, and 62 healthy young men by utilizing a multistage treadmill test of maximal exercise. With aging alone, duration of exertion and maximal exercise heart rate were diminished while maximal systolic pressure increa...

The relative contributions of aging and coronary heart disease to the impairment of functional capacity were assessed in 117 coronary patients, 117 age-matched healthy middle-aged men, and 62 healthy young men by utilizing a multistage treadmill test of maximal exercise. With aging alone, duration of exertion and maximal exercise heart rate were diminished while maximal systolic pressure increa...