OBJECTIVE To determine if cervical cerclage reduces the rate of spontaneous early preterm birth in cases of dichorionic-diamniotic (DCDA) twin gestation with an ultrasound-detected short cervix. METHODS This was a retrospective cohort study of 40 consecutive DCDA twin gestations at Saint Peter's University Hospital from November 2006 to November 2014 in which cervical cerclage was performed f...

Sri Lanka is an island with genetic diversity between the five main population groups. Our twin registry is the first in the developing world. Initially, we established a volunteer cohort of 4600 twin pairs through a competition advertised in the media. In addition, we have volunteer cohorts, birth registration-based cohorts through hospitals, and community-based cohorts. There is also a nation...

size from birth to 5 years in a population-based twin cohort were studied. Sex differences in gene–environment etiology were also explored. Analyses used data from the Quebec Newborn Twin Study (QNTS), a population-based birth cohort of 672 twin pairs. The final sample consisted of 177 complete twin pairs. Heritability of weight was moderate at birth while common environmental factors accounted...

BACKGROUND Preterm birth is the principal factor contributing to adverse outcomes in multiple pregnancies. Randomized controlled trials of progestogens to prevent preterm birth in twin pregnancies have shown no clear benefits. However, individual studies have not had sufficient power to evaluate potential benefits in women at particular high risk of early delivery (for example, women with a pre...

DESIGN To study the association between mode of delivery and neonatal mortality in second twins. To study the association between caesarean delivery and mortality with minimum bias of the indication for the operation, we wanted to compare the outcome of second twins delivered by caesarean due to breech presentation of the sibling with vaginally delivered second twins in uncomplicated pregnancie...

OBJECTIVES The objectives of the study were to determine the outcome of twin births at the University of Maiduguri Teaching Hospital (UMTH), Maiduguri, in terms of morbidity and mortality and to recommend possible measures to curtail or reduce some of the preventable complications. MATERIALS AND METHODS This is a 5-year retrospective study, from January 2000 to December 2004, of twin births a...

OBJECTIVE To determine the effect of birth order on the risk of perinatal death in twin pregnancies. DESIGN Retrospective cohort study. SETTING England, Northern Ireland, and Wales, 1994-2003. PARTICIPANTS 1377 twin pregnancies with one intrapartum stillbirth or neonatal death from causes other than congenital abnormality and one surviving infant. MAIN OUTCOME MEASURES The risk of perin...

A consistent finding from twin studies is that the environment shared by family members does not contribute to the variation in susceptibility to asthma. At the same time, it is known that environmental risk factors that are shared by family members are associated with the liability for asthma. We hypothesize that the absence of a main effect of shared environmental factors in twin studies can ...

Objectives: To find out the maternal and fetal complications of twin gestation and to assess the effect of these complications on perinatal outcome. Material and Methods: This Descriptive study was carried out in Gynae B Unit of Khyber Teaching Hospital, Peshawar from January 2010 to December 2010. A total of 50 patients with twin pregnancy who had completed 28 weeks of twin gestation both book...

BACKGROUND Symptoms of congenital cytomegalovirus infection remains unclear. CASE CHARACTERISTICS Extremely low birth weight twins with twin-to-twin transfusion syndrome were infected with cytomegalovirus congenitally. OBSERVATION The donor showed neuronal impairment, whereas the recipient showed hepatic dysfunction. MESSAGE Intrauterine hemodynamics may be important in pathophysiology of...