Ribonucleases are central components of the eukaryotic RNA processing and decay machineries. They participate in processing of stable RNA species and pre-mRNA molecules as well as remove unwanted molecules like: RNA processing by-products and malformed RNA species that are identified by surveillance pathways. Finally, ribonucleases participle in mRNA turnover and regulated mRNA decay pathways. ...

The article reports on the new technology and equipment of vertical‑stack molding (VSM), created by OJSC “BELNIILIT” for manufacture molds. development is intended production molds cast blanks oil, which are later used piston rings internal combustion engines. difference between above‑mentioned traditional methods VSM use models without drafts. export‑oriented has a great economic effect ring m...

In this paper, we present nonmonotone methods for feedforward neural network training, i.e. training methods in which error function values are allowed to increase at some iterations. More specifically, at each epoch we impose that the current error function value must satisfy an Armijo-type criterion, with respect to the maximum error function value of M previous epochs. A strategy to dynamica...

In our previous paper, we have proposed a framework for automatically translating tree-processing programs into stream-processing programs. However, in writing programs that require buffering of input data, a user has to explicitly use buffering primitives which copy data from input stream to memory or copy constructed trees from memory to an output stream. Such explicit insertion of buffering ...

Recent exponential increase of protein sequences creates a challenge for automated annotation methods. When sequence based methods (e.g. PSIBLAST [1]) fail to identify a possible homologue (generally below 25% of protein identity i.e. within so-called twilight zone), fold recognition methods offers additional sensitivity [2,4,5,8]. However, training, validating and comparing fold recognition pe...

Four methods have been presented to determine the semantic similarity of two GO terms based on the annotation statistics of their common ancestor terms (Resnik [1], Jiang [2], Lin [3] and Schlicker [4]). Wang [5] proposed a new method to measure the similarity based on the graph structure of GO. Each of these methods has its own advantages and weaknesses. GOSemSim package [6] is developed to co...

We discuss the relevance of coherent states based methods in signal processing applications, and illustrate with a couple of practical examples, namely problems of waveform detection in a noisy environment, and problems of spectral analysis for non stationary time series.

Mathematical processing of images in real-time vision systems can be conventionally divided into two stages: preprocessing (filtering, contrasting, protection from natural distortions, etc.) and final one (imposition, visualization, solution of the navigation task, etc.). Mentioned tasks can be solved by a lot of known and specially developed methods with various degrees of efficiency. The pres...

the parafascicular nucleus (pfn) of thalamus, as a supraspinal structure, has an important role in processing of nociceptive information. in addition, μ-opioid receptor contributes to supraspinal modulation of nociception. in the present study, the effects of microinjection of naloxone (a non-specific opioid-receptor antagonist) and naloxonazine (a specific μ-opioid receptor antagonist) were in...