AIM To compare the efficacy of using covered self-expandable metal stents (CSEMSs) and uncovered self-expandable metal stents (UCSEMSs) to treat objective jaundice caused by an unresectable malignant tumor. METHODS We performed a comprehensive electronic search from 1980 to May 2015. All randomized controlled trials comparing the use of CSEMSs and UCSEMSs to treat malignant distal biliary obs...

BACKGROUND Two pertussis toxin sensitive G(i) proteins, G(i2) and G(i3), are expressed in cardiomyocytes and upregulated in heart failure. It has been proposed that the highly homologous G(i) isoforms are functionally distinct. To test for isoform-specific functions of G(i) proteins, we examined their role in the regulation of cardiac L-type voltage-dependent calcium channels (L-VDCC). METHOD...

Two immortalized human juvenile chondrocyte cell lines, T/C28a2 and C28/I2, were employed to determine the extent to which recombinant human (rh) IL-6 or rh-TNF-α increased the production of matrix metalloproteinase-9 (MMP-9). The effect of rhIL-6 on neutrophil gelatinase-associated lipocalin (NGAL) was also assessed. Although C28/I2 chondrocytes incubated with rhIL-6 (50 ng/ml) increased MMP-9...

beta-N-Acetylhexosaminidase I2 was purified from human liver by a combination of concanavalin A chromatography, DEAE-cellulose chromatography, gel filtration and affinity chromatography on 2-acetamido-N-(6-aminohexanoyl)-2-deoxy-beta-D-glucopyranosylamine coupled to CNBr-activated Sepharose 4B. Its specific activity was 130 mumol/min per mg of protein compared with values of 150 and 320 mumol/m...

We hypothesize tha t prostacyclin (PG I2) is an anti-atherosclerotic hormone and that atherosclerosis develops when endothelial P G I2 synthetase is inhibited by lipid peroxides. Serum lipid peroxides occur in low-density lipoproteins (LDL). LDL lipid peroxides are elevated in common types of hyperlipoproteinaemias, P G I2 generation is im paired in atherosclerosis, and infusion of synthetic P ...

in order to study the effect of planting arrangements and water quantities in drip irrigation onyield of maize, an experiment was carried out using a spilt block based on randomizedcomplete block design for three years (2006-09) in moghan. the factorial experiment hadthree planting densities (75000, 85000 and 95000 plants per hectare ) with one- and two-rowscultivation (b1= one row cultivation ...

We have previously demonstrated that growth of embryonic chick atrial cells in medium supplemented with lipoprotein-depleted serum (LPDS) resulted in a coordinate increase in the expression of genes involved in the parasympathetic response of the heart (the M2 muscarinic receptor; the -subunit of the heterotrimeric G protein, G i2; and the inward rectifying K channel protein, GIRK1) and a marke...

Let m ≥ 0 be the smallest integer such that S ∩ Ti−a+(m−1)(b−a) = Ø or i+b+m(b−a) ≥ a+c. If S∩Ti−a+(m−1)(b−a) = Ø, let i2 = i−a+(m−1)(b−a). Otherwise, let i2 = i+b+m(b−a). If it is the former case, then m ≥ 1 and i2 ∈ I (since i + b + (m− 1)(b− a) < a + c, so i2 = i− a + (m− 1)(b− a) < c− b = a). We now show that if it is the latter case, then i2 ∈ U . Assume i2 = i + b + m(b− a). Then i + b + ...

The specialty of radiation therapy has increased in complexity over the years, yet as technology improves, the goal of improving outcomes while decreasing toxicity remains critical. Malignant gliomas remain among the most devastating of all malignancies, yet as conventional treatments (surgery, radiation, and chemotherapy) have become optimized overall survival has improved. The underlying mole...