نتایج جستجو برای: type calcium channels
تعداد نتایج: 1590321 فیلتر نتایج به سال:
To study the molecular pharmacology of low-voltage-activated calcium channels in biophysical detail, human medullary thyroid carcinoma (hMTC) cells were investigated using the single-channel technique. These cells had been reported to express T-type whole-cell currents and a Ca(v)3.2 (or alpha 1H) channel subunit. We observed two types of single-channel activity that were easily distinguished b...
Among the family of voltage-gated calcium channels, low threshold T-type channels have only recently joined their high threshold N-type channel brother in being generally accepted as molecular players within pain signaling. The ability of T-type channels to modulate neuronal excitability at low thresholds has implications concerning their participation in pain neurotransmission at multiple leve...
Infection is a significant cause of preterm birth. Abnormal changes in intracellular calcium signals are the ultimate triggers of early uterine contractions that result in preterm birth. T‑type calcium channels play an important role in the pathogenesis of cancer, as well as endocrine and cardiovascular diseases. However, there are limited studies on their role in uterine contractions and partu...
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