Since the introduction of 3 adrenoceptor antagonists into clinical practice approximately 30 years ago, these drugs have been regarded as being contraindicated in patients with severely depressed ventricular function because of the risk of precipitating haemodynamic deterioration. It may therefore seem both surprising and paradoxical that the idea of using 0 blockers as a primary therapy for co...

t a b e Obesity as reached epidemic proportions globally, with approximately one-half billion people (12% of the world’s population) considered obese (1). In the United States alone, the prevalence of obesity has increased by 50% in the past 30 years to where now 70% of all adults are classified as either overweight or obese (2). More sobering is that 30% of all children between 2 and 19 years ...

Field observations indicate that left turning vehicles at U-turn sections lead to a significantly bottleneck (congestion) both origin and destination (opposing) roads. The bottlenecks have been observed in several U-turns such as Kufa –Najaf sections, Najaf –Karbala sections. It was found turn flow from leads high congestion on Therefore, field improvements done by the traffic policemen who cre...

In Germany the performance of opening the electricity markets proves to be poor. While the sector’s productivity nearly doubled, the customers were left out in the cold. In actuality, the generated redistribution mass remained in the firms. There, the management used the threat of competition as an instrument for rationalisation and for the moderation of wage growth, while it simultaneously and...

Integration host factor (IHF) is a small heterodimeric protein that specifically binds to DNA and functions as an architectural factor in many cellular processes in prokaryotes. Here, we report the crystal structure of IHF complexed with 35 bp of DNA. The DNA is wrapped around the protein and bent by >160 degrees, thus reversing the direction of the helix axis within a very short distance. Much...

Reinforced concrete stair slabs with mid landings i.e. Dog-legged shaped are conventionally designed as per specifications of standard codes of practices which guide about the effective span according to the varying support conditions. Presently, the behavior of such slabs has been investigated using Finite Element method. A single flight stair slab with landings on both sides and supported at ...

We construct a class of representations of the quadratic R-matrix algebra given by the reflection equation with the spectral parameter, R (u − v)T (u)R (u + v)T (v) = T (v)R (u + v)T (u)R (u − v), in terms of certain ordinary difference operators. These operators turn out to act as parameter shifting operators on the 3F 2(1) hypergeometric function and its limit cases and on classical orthogona...