OBJECTIVE The purpose of this study was to determine which demographic, clinical, and treatment factors influenced chronic pressure ulcer healing, and to identify the implications for pressure ulcer care being delivered in skilled nursing facilities. DESIGN A multisite retrospective chart review was conducted using a structured data abstraction form and protocol. SETTING Data collection too...

introduction & objective: in vitro studies shown the effect of zinc sulfate on healing of ulcers but limited in vivo studies have been done to demonstrate this effect in human. this study was conducted to investigate the effect of zinc sulfate on peptic ulcer disease materials & methods: this is a double blind randomized clinical trial study. we studied people who referred to endoscopy clinic i...

BACKGROUND To determine the effect of aspirin on ulcer healing rate in patients with chronic venous insufficiency, and to establish prognostic factors that influence ulcer evolution. METHODS Between 2001 and 2005, 78 patients with ulcerated lesions of diameter >2 cm and associated with chronic venous insufficiency were evaluated in our hospital. Of these, 51 patients (22 men, 29 women) with m...

Diabetic ulcers on the lower extremities present a difficult treatment problem, and some ulcers respond poorly to conventional topical and cast treatment. The purpose of this study was to assess the effect of cultured allogeneic keratinocyte epithelium and fibroblast-gelatin sponge on the healing of chronic, refractory diabetic leg and foot ulcers. Non-diabetic chronic leg ulcers were treated f...

OBJECTIVES To compare the clinical effectiveness and cost-effectiveness of larval therapy with a standard debridement technique (hydrogel). DESIGN A pragmatic, three-arm, randomised controlled trial with an economic evaluation. SETTING Community nursing services, community leg ulcer clinics and hospital outpatient leg ulcer clinics. A range of urban and rural settings. PARTICIPANTS Patien...

BACKGROUND Chronic wounds are managed almost entirely by community nurses. Almost all individuals with leg ulcers report acute pain usually related to dressing change. Little is known about pain after healing. The purpose of this study was to explore the course of pain from baseline to time of healing of leg ulcers (venous or mixed etiology). In order to understand this phenomenon and develop i...

An ulcer is a break in the durability of epithelium, either skin or mucus membrane due to cellular death. Wound simply disruption any tissue-soft tissue bone internal organ i.e. structurally and functionally. Ulcer continuity layer skin. one type wound.Non healing cutaneous ulcers are commonly seen diabetes, vascular insufficiency, other chronic conditions, this global health concern which cont...

Helicobacter pylori (H. pylori) eradication therapy alone is insufficient to ensure healing of large ulcers with H. pylori-positive gastric ulcer (GU). The question of what is the optimum antiulcer treatment following H. pylori eradication therapy has not been fully elucidated. Furthermore, the ulcer healing effects of eradication therapy itself with H. pylori-positive duodenal ulcer (DU) have ...

OBJECTIVE To determine the effect of oxpentifylline on the healing of venous ulcers of the leg. DESIGN Double blind, randomised, prospective, placebo controlled, parallel group study. SETTING Four outpatient clinics treating leg ulcers in England and the Republic of Ireland. PATIENTS 80 Consecutive patients with clinical evidence of venous ulceration of the leg in whom appreciable arteria...

This study was undertaken in order to follow up ulcer healing, ulcer recurrence, nutritional status and life-situation in elderly patients with leg ulcers. Of 70 patients assessed previously in 1996, 43 (61%) were still alive in 2000 and, of these, 38 (88%) participated in the follow-up. Rate of healing, recurrence and amputation were obtained from medical records and interviews with the patien...