Background: Pre-eclampsia (PE) is a multisytemic disorder originating from the placenta with high prevalence in sub-Saharan Africa. Early (<34 weeks) and late (>34 – onset PE have different maternal perinatal outcomes overlapping clinical features. Differences Doppler velocimetry pattern these subgroups appears unsettled.Methods: In prospective cohort study, 110 pregnant women singleton p...

Endothelial cells were isolated from arteries and veins obtained from elderly people at autopsy and propagated for 37 to 69 population doublings. The cells secreted tissue-type plasminogen activator (t-PA) and PA inhibitor-1, and, after subculturing, urokinase-type PA (u-PA) antigen. The following differences between endothelial cells from adult arteries and veins were observed: 1) The cells ha...

The umbilical artery was chosen as a possible model for evaluating the vascular injury provoked by tobacco smoking in humans. Cords from newborn children delivered by 15 nonsmoking and 13 smoking mothers were studied in the transmission and the scanning electron microscope. Pronounced intimal changes were seen in the arteries from smoking mothers; the most important findings were degenerative c...

BACKGROUND The use of decellularized biological scaffolds for the reconstruction of small-diameter vascular grafts remains a challenge in tissue engineering. Thrombogenicity is an important cause of obstruction in these vessels due to decellularization. Seeding of the decellularized vascular constructs with endothelial cells is therefore a prerequisite for the prevention of thrombosis. The aim ...

The introduction of Doppler velocimetry to obstetrics offered a noninvasive and safe imaging modality of indirectly assessing the fetal and uteroplacental circulation. Obstetric Doppler ultrasound plays an important role in detecting Intra Uterine Growth Restriction (IUGR). The early diagnosis of IUGR with the help of abnormal flow patterns in umbilical, uterine and middle cerebral arteries usi...

INTRODUCTION: Endometriosis, commonly occurs in the pelvic organs, mostly the ovaries, with dysmenorrhea, menorrhagia Umbilical endometriosis is rare .Symptoms include umbilical masses with swelling and pain.. SO it is often not recognized  based on  its clinical appearance. PRESENTATION OF CASE: A 32-year old female, was presented  with  umbilical bulging and  mild cyclic umblical  pain. with...

Bradykinin (BK) and serotonin (5-HT) are vasoactive agents that significantly contribute to the normal functioning of fetoplacental blood flow, including modulation of smooth muscle tone in umbilical vein and arteries. Accordingly, umbilical artery is a crucial component of fetoplacental circulation with the vital function of providing suitable perfusion and nutrition for placenta. The aim of t...