BACKGROUND Endothelial cell co-culture assays are differentiation assays which simulate the formation of capillary-like tubules with the aid of a supportive cell layer. Different cell types have been employed as a supportive cell layer, including human pulmonary artery smooth muscle cells (PASMCs) and human mammary fibroblasts. However, these sources of human tissue-derived cells are limited, a...

A neonate developed complete thrombosis of the abdominal aorta after catheterisation of the umbilical artery. This was successfully treated with an intravenous infusion of streptokinase.

Using a mid- to late-gestation ovine model of intrauterine growth restriction (IUGR), we examined uteroplacental blood flow and fetal growth during melatonin supplementation as a 2 × 2 factorial design. At day 50 of gestation, 32 ewes were supplemented with 5 mg of melatonin (MEL) or no melatonin (CON) and were allocated to receive 100% [adequate; (ADQ)] or 60% [restricted (RES)] of nutrient re...

11 McParland P, Steel SA, Pearce JMF. The clinical implications of absent or reversed end-diastolic frequencies in the umbilical artery flow velocity waveforms. EurJI Obstet Gynecol Reprod Biol 1991; 37: 15-23. 12 Fleischer A, Schulman H, Farmakides G, Bracero L, Blattner P, Randolph G. Umbilical artery velocity waveforms and intrauterine growth retardation. Am J Obstet Gynecol 1985; 151: 502-5...

To evaluate the influence of cow breed and number of fetuses on uterine and umbilical blood flows and nutrient fluxes or uterine tissues from gravid cows, surgery was performed on Charolais or Hereford cows with single or twin fetuses at 177 +/- .2 d (mean +/- SEM) after mating. Indwelling catheters were placed in a fetal femoral artery and vein, in an umbilical vein of each fetus, and in a ute...

Objective: To evaluate the screening efficiency of ultrasound and Doppler measurements in the prediction of fetal anemia in alloimmunized pregnancies. Materials and Method: In a prospective study, 24 nonhydropic fetuses with red blood cell alloimmunization were evaluated with ultrasound and Doppler imaging. Middle cerebral artery peak systolic velocity, intrahepatic umbilical venous maximum vel...

Objective: To assess the impacts of dexamethasone given to the mother on fetal Doppler flow velocity waveforms of both umbilical and fetal middle cerebral arteries in pregnancies with normal fetoplacental vascular resistance. Study Design: Prospective Study. Patients and Methods: Pregnant women between 28 weeks and 34 weeks gestation at risk of preterm labour, Preterm birth was anticipated on t...

To determine and compare accuracy of various Doppler parameters for perinatal outcome. Umbilical artery (UA), Middle cerebral artery (MCA) and Ductus Venosus for predicting adverse perinatal outcome in patients of intrauterine growth retardation (IUGR) and pregnancy induced hypertension (PIH). 60 singleton pregnancy with clinically suspicion of IUGR/PIH or both, having gestational age of 30 wee...