total serum copper levels of 70 pregnant women hospitalized for delivery at misaghieh (private), 90 at farah (public) maternity hospitals immediately after delivery and 27 non-pregnant women (control) were measured. the copper level in the blood serum of umbilical cord of the newborn infants was also determined. the copper levels were significantly elevated in both pregnant groups as compared t...

Background: Due to high differentiation potential and self-renewality, Mesenchymal Stem Cells are now widely considered by researchers in several diseases. FBS is used as a supplement in culture media for proliferation, differentiation, and other culture processes of MSCs, which is associated with transmission risk of a variety of infections as well as immune responses. PRGF derived from platel...

Plasma concentrations of B-type na-triuretic peptide (BNP), a 32-amino acid peptide hormone secreted by the myocardium, increase in response to myocardial stretch or strain (1, 2). On secretion, proBNP, the storage form of BNP, is cleaved into the inactive N-terminal proBNP (NT-proBNP) and the endocrinologi-cally active BNP. In patients with heart failure, plasma BNP concentrations are related ...

PURPOSE To investigate the efficacy of umbilical cord serum eyedrops for the treatment of neurotrophic keratitis. DESIGN Prospective noncomparative case series. PARTICIPANTS Twenty-eight eyes of 28 patients with neurotrophic keratitis who were refractory to conventional treatment. METHODS The patients with neurotrophic keraitis were treated with 20% umbilical cord serum eyedrops 6 to 10 t...

To clarify the maternal-fetal transfer of mercury across the placenta, inorganic and organic mercury were determined in 41 paired samples of maternal blood, placenta, umbilical cord blood and umbilical cord obtained from pregnant women who had no particular exposure to mercury compounds in their history. Both inorganic and organic mercury were detected in all the samples but the ratio of organi...

Interest in umbilical cord blood as an alternative source of hematopoietic stem cells is growing rapidly. Umbilical cord blood offers the clinician a source of hematopoietic stem cells that are readily available and rarely contaminated by latent viruses. Moreover, the collection of umbilical cord blood poses no risk to the donor; there is no need for general anesthesia or blood replacement, and...

OBJECTIVE To investigate the effect of umbilical cord milking on hematological parameters at 6 weeks of age in late preterm neonates. DESIGN Randomized controlled trial. SETTING A tertiary care center of Northern India during 2013-14. PARTICIPANTS 200 moderate to late preterm neonates randomly allocated to early cord clamping or umbilical cord milking group (100 in each). INTERVENTION I...

OBJECTIVE Although mesenchymal stem/stromal cells represent a promising therapeutic strategy for acute respiratory distress syndrome, clinical translation faces challenges, including scarcity of bone marrow donors, and reliance on bovine serum during mesenchymal stem/stromal cell proliferation. We wished to compare mesenchymal stem/stromal cells from human umbilical cord, grown in xeno-free con...

Introduction: The purpose of this study was to compare the topical effect of breast milk, chlorhexidine, and dry cord care on the umbilical cord bacterial colonization in premature infants hospitalized in a neonatal intensive care unit. Methodology: This randomized controlled double-blinded trial was performed on premature infants admitted to the NICU of Valiasr Hospital, Birjand in 2016.  The...

The pharmacokinetics of amoxicillin were studied in umbilical cord and neonatal sera relative to maternal concentrations in prevention of neonatal group B streptococcus infection. The subjects were 44 pregnant women receiving amoxicillin as 1 or 2 g as an intravenous infusion. To measure the concentrations, blood samples were obtained from the mother, the arterial and venous umbilical cord, and...