Herein, we describe the concise synthesis of 2,6-cis-substituted tetrahydropyran derivatives based on a domino olefin cross-metathesis/intramolecular oxa-conjugate cyclization (CM/IOCC) reaction. We have found that the domino CM/IOCC of δ-hydroxy olefins with α,β-unsaturated carbonyl compounds (e.g., trans-crotonaldehyde or N-acryloyl-2,5-dimethylpyrrole) could be efficiently achieved in the pr...

Microalgae oil serves as a feedstock for a biorefinery approach to mid-chain (di-)carboxylic acid esters, currently only accessible via demanding synthetic routes. Via the butenolysis of monoand poly-unsaturated fatty acids, short-chain unsaturated fatty acid methyl esters and monoand di-enes were produced in a high selectivity. These olefins were further processed into value added linear mid-c...

Relatively few studies have been made on the lipide metabolism of Penicillium chrysogenum, although large quantities of these compounds are used as antifoam agents in the production of penicillin. Goldschmidt and Koffler (1) demonstrated that unsaturated long chain fatty acids present in the antifoam were responsible for stimulation of penicillin yields, since many physiologically inert compoun...

4.2.8. Reductive Coupling 3109 5. Reaction of Aromatic Compounds 3110 5.1. Electrophilic Substitutions 3110 5.2. Radical Substitution 3111 5.3. Oxidative Coupling 3111 5.4. Photochemical Reactions 3111 6. Reaction of Carbonyl Compounds 3111 6.1. Nucleophilic Additions 3111 6.1.1. Allylation 3111 6.1.2. Propargylation 3120 6.1.3. Benzylation 3121 6.1.4. Arylation/Vinylation 3121 6.1.5. Alkynylat...

The title epoxide was obtained by spontaneous epoxidation of the corresponding unsaturated imide in air or peracid oxidation. Unambiguous assignment 1H- and 13C-NMR spectra is achieved comparison between analogous compounds its X-ray structure confirms exo,exo-configuration.

in some special cases, rubber compounds with high amounts of unsaturated elastomer are recommended with organic sulfur donors instead of mineral sulfurs. in this condition, activated sulfur is produced in situ and curingprocess is facilitated without accelerators. organic sulfur donor compounds have low thermal stability and in the vulcanization temperature produce free and activated sulfurs. t...

2-Tosylacetonitrile (1) when reacted with α,β-unsaturated nitriles 2a-c or a mixture of formaldehyde and 3-amino-2-substituted-pent-2-endinitriles 6a,b yielded pyridine derivatives 3a-c and 9a,b, respectively, while when subjected to react with salicylaldehyde yielded chromene derivatives 4 and 5, subsequently. The behavior of thiocarbamoyl derivative 10 derived from 1 towards some α-halogenate...

Plant endophytic microorganisms represent a largely untapped resource for new bioactive natural products. Eight polyketide natural products were isolated from a mangrove endophytic fungus Phomosis sp. A818. The structural elucidation of these compounds revealed that they share a distinct feature in their chemical structures, an oxygen-bridged cyclooctadiene core skeleton. The study on their str...

Chemical investigation of a sample of propolis originating from North-Western Cameroon led to the isolation of thirteen alk(en)ylphenols (1-13) (inseparable mixture) along with α-amyrin (14), β-amyrin (15), lupeol (16), cycloartenol (17), mangiferonic acid (18), ambonic acid (19), mangiferolic acid (20), ambolic acid (21), isomangiferolic acid (22) and nine alk(en)ylresorcinols (23-31) (insepar...

This study describes the reduction of functionalised model compounds to their corresponding hydrocarbons by catalytic hydropyrolysis to provide information on the release of biomarkers fromkerogens and asphaltenes covalently bound through the functional groups investigated. Five model compounds were investigated, the n-C18 carboxylic acids, stearic and oleic acids; the C24 steroidal acid, 5b-ch...