Linear ion-trap (LIT) MS2 mass spectrometric approach toward locating the position of double bond(s) of unsaturated long-chain fatty acids and toward discerning among isomeric unsaturated fatty acids as dilithiated adduct ([M-H+2Li]+) ions are described in this report. Upon resonance excitation in a LIT instrument, charge-remote fragmentation that involves beta-cleavage with gamma-H shift (McLa...

BACKGROUND Type 2 diabetes is associated with increased plasma concentrations of non-esterified fatty acids (NEFAs), which trigger pancreatic β-cell dysfunction and apoptosis. Only long-chain saturated NEFAs induced lipotoxicity in rat insulin-producing cells in in vitro experiments, whereas unsaturated NEFAs were not toxic. Some unsaturated NEFAs even protected against lipotoxicity. In former ...

Coal mining originates environmental impacts on soil and water bodies, including the leaching of Potentially Toxic Elements (PTEs) Polycyclic Aromatic Hydrocarbons (PAHs) in mine waste piles. This research aims to identify characterize changes induced by self-burning Technosols from a coal pile means comprehensive hydropedological assessment encompassing geochemical, mineralogical, hydrological...

The fatty acid profile of vegetable oils (VOs), together with the poor ability of marine fish to convert polyunsaturated fatty acids (PUFA) to highly unsaturated fatty acids (HUFA), lead to important changes in the nutritional value of farmed fish fed VO, which include increased fat and 18:2n-6 and reduced n-3 HUFA. Echium oil (EO) has a good n-3/n-6 balance as well as an interesting profile wi...

This study compared the molecular lipidomic profile of LDL in patients with nondiabetic advanced renal disease and no evidence of CVD to that of age-matched controls, with the hypothesis that it would reveal proatherogenic lipid alterations. LDL was isolated from 10 normocholesterolemic patients with stage 4/5 renal disease and 10 controls, and lipids were analyzed by accurate mass LC/MS. Top-d...

The cuticle of Drosophila consists of long chain, unsaturated hydrocarbons that have pheromonal properties. These pheromones are used for recognition of the opposite sex and are responsible for mating recognition between closely related species. The chromosomal basis for the difference in pheromone profile between two closely related species D. sechellia and D. simulans has been previously exam...

The aim of the present study was to evaluate effects dietary ricinoleic acid from castor oil on milk yield, composition, fatty profile and haemato-biochemical in lactating Kankrej cows. Twenty cows were assigned following groups: control (CON), basal diet without any additive treatment (RAS), with 2 g/animal/day oil. Dietary had no (P>0.05) effect dry matter intake feed efficiency. Milk yiel...

A cholesterol-enriched diet has been shown to adversely affect lipoprotein profiles and increase cardiovascular disease risk. Dietary cholesterol plays an important role in modulating inflammatory responses involved in atherosclerosis. In the present study, the effect of Oryctes rhinoceros larva oil (ORO), an unsaturated fatty acid-rich animal fat, on serum lipid profile and some proinflammator...

Situations including premature infants, or those in which there is a rejection to breastfeeding, require the use infant formulas for total or partial replacement of human milk. The objective of this study was to determine the lipid content and to identify the lipid profile of infant formulas. Samples were collected from ten different infant formulas, used as a substitute for breast milk at the ...

BACKGROUND & AIMS In this study we report the effects of sunflower, virgin olive and fish oils on the lipid profile and antioxidant defence system in liver mitochondria from rabbits with experimental atherosclerosis. METHOD An atherogenic control group were fed for 50 days on a diet containing 3% lard and 1.3% cholesterol. Four groups were fed for an additional period of 30 days with a diet e...