BACKGROUND Anencephaly is a fatal congenital abnormality characterised by absence of cerebral hemisphere and cranial vault. Overall incidence of anencephaly is 3.8-6.0/1,000 births. This study was conducted to determine the prevalence, diagnosis and management of anencephaly in District Swat. METHODS This prospective study was carried out over a period of one year from January 2007 to Decembe...

BACKGROUND Women undergoing hysterectomy for benign uterine disease (BUD) may experience stress urinary incontinence (SUI). We performed tension-free vaginal tape (TVT) procedure and laparoscopic-assisted vaginal hysterectomy (LAVH) simultaneously and assessed the feasibility and efficacy of TVT performed under general anesthesia and the resultant anti-incontinence effects following the combine...

Received January 2008 Accepted July 2008 INTRODUCTION Endometriosis is defined as abnormal growth of the endometrial glands and stroma beyond the normal confines of the uterus. Although the condition is usually limited to the ovaries, uterosacral ligaments, and Douglas’ pouch, it has been reported in almost every organ of the body. A total of 10% to 20% of women in reproductive ages may be affe...

OBJECTIVE To determine the efficacy and safety of the herbal formula Phyto-Female Complex (SupHerb, Netanya, Israel; ingredients: standardized extracts of black cohosh, dong quai, milk thistle, red clover, American ginseng, chaste-tree berry) for the relief of menopausal symptoms. METHODS A randomized, double-blind, placebo-controlled trial in 50 healthy pre and postmenopausal women, aged 44-...

Background. Placenta accreta is a potentially life-threatening obstetrical condition and is responsible for many emergency Caesarean hysterectomies. Early prenatal diagnosis may help minimize maternal morbidity and mortality. This report highlights risk factors, early diagnostic findings and complications associated with placenta accreta, and the role of first trimester sonography in diagnosis....

Aggressive chemotherapy and radiotherapy generally result in the loss of both endocrine and reproductive functions. In 1990, a woman aged 20 years, presenting with beta-thalassemia major, underwent chemotherapy (busulfan and cyclophosphamide) and total body irradiation (TBI) before bone marrow transplantation (BMT), the donor being her 17-year-old HLA-compatible sister. The treatment resulted i...

Hydrometrocolpos is a rare congenital disorder consisting of cystic dilation of the vagina and uterus and accumulation of mucus secretions resulting from genital tract obstruction.1 The obstruction can be produced by imperforate hymen, transverse vaginal membrane, or some degree of vaginal atresia.2 Excessive intrauterine stimulation of the cervical mucus glands by circulating maternal estrogen...

Purpose: Placenta increta in early pregnancy is rare and has been documented in only few cases and is a complication of pregnancy that can be life threatening for both mother and fetus. Thus early diagnosis of this problem is very important. This problem is a result of inadequate development of the decidua. Case Presentation: A 26 years old woman (gravid 3, para 2) with history of cesarean sect...

A 34-year-old pregnant Turkish woman was admitted to the emergency service because of contractions at 33 weeks. Her vaginal examination revealed 8-9 cm cervical dilatation and 80-90% effacement. Fetal membranes were intact, and the fetus had a vertex presentation. Shortly after, she had a vaginal delivery. The newborn had mid-facial cleft, low-set ears, cleft lip, bilateral pterygia, ambiguous ...

Background: Neural tube defects are common and major birth defects. Their incidence varies according to the geographic conditions, race, sex of the baby and certain maternal conditions. This study was conducted to determine the incidence of neural tube defects and its risk factors in Peshawar. Material and Methods: It was retrospective study of deliveries at Gynae A unit of Lady Reading Hospita...