نتایج جستجو برای: vascular abnormality

تعداد نتایج: 363003  

Journal: :Thorax 1962
B T LE ROUX

The sequestration within the lung of a mass of abnormal pulmonary tissue, the blood supply to which is systemic and not pulmonary, is an uncommon but clinically recognizable entity. The clinical and pathological features are reproduced from case to case with remarkable consistency, and it is important to recognize the condition because it produces symptoms, is amenable to surgical correction, a...

2014
Yasuhiro Funahashi Kiyoshi Okamoto Yusuke Adachi Taro Semba Mai Uesugi Yoichi Ozawa Osamu Tohyama Taisuke Uehara Takayuki Kimura Hideki Watanabe Makoto Asano Satoshi Kawano Xavier Tizon Paul J McCracken Junji Matsui Ken Aoshima Kenichi Nomoto Yoshiya Oda

Eribulin mesylate is a synthetic macrocyclic ketone analog of the marine sponge natural product halichondrin B and an inhibitor of microtubule dynamics. Some tubulin-binding drugs are known to have antivascular (antiangiogenesis or vascular-disrupting) activities that can target abnormal tumor vessels. Using dynamic contrast-enhanced MRI analyses, here we show that eribulin induces remodeling o...

2011
Jang-Whan Bae

Hypertension is a very common but incompletely understood disease, especially in its pathogenesis and vascular complications occurring in the cardiovascular research filed. There are many explanations for pathological mechanisms in hypertension, including adrenergic over-reactivity, renin-angiotensin-aldosteron system abnormality and constitutionalgenetic-environmental factors. Recently emergin...

1999
George S. Alexopoulos Martha L. Bruce David Silbersweig Balu Kalayam Emily Stern

We have suggested that cerebrovascular disease may predispose, precipitate, or perpetuate some late-life depressive syndromes. The mechanisms of "vascular depression" include disruption of cortico-striato-pallido-thalamo-cortical (CSPTC) pathways or their modulating systems. This view is supported by the presentation of vascular depression, which consists of depressive symptoms, cognitive abnor...

Journal: :Diabetes 2008
Maria Teresa Gentile Carmine Vecchione Gennaro Marino Alessandra Aretini Alba Di Pardo Giovanna Antenucci Angelo Maffei Giuseppe Cifelli Luca Iorio Alessandro Landolfi Giacomo Frati Giuseppe Lembo

OBJECTIVE Since vascular dysfunction is a main trait of obese subjects, in the present study we evaluated the vascular impact of resistin, a recently discovered hormone markedly increased in obesity. RESEARCH DESIGN AND METHODS We performed our analysis on aortic and mesenteric segments from young and old C57BL/6 mice and on cultured endothelial cells. Resistin-induced vascular effect was eva...

Journal: :bulletin of emergency and trauma 0
shahram bolandparvaz trauma research center, shiraz university of medical sciences, shiraz, iran. behzad ghaffari trauma research center, shiraz university of medical sciences, shiraz, iran. seyed mohsen mousavi trauma research center, shiraz university of medical sciences, shiraz, iran. shahram paydar trauma research center, shiraz university of medical sciences, shiraz, iran. hamid reza abbasi trauma research center, shiraz university of medical sciences, shiraz, iran.

objective: to evaluate the predictive value of some biochemical markers in the outcome of extremity vascular trauma. methods: this study comprised 30 patients with traumatic arterial injury and acute limb ischemia referred to namazi hospital affiliated with shiraz university of medical ssciences, over a period of 8 months, from sep 2009 to jul 2010. venous blood samples were drawn from distal i...

Journal: :Journal of pharmaceutical research international 2021

Aim of Object: During the COVID-19 pandemic, entire world is experiencing a mortality situation; most people are battling against corona virus, but some individuals have already suffered from cardiovascular problems.
 For improved patient care, adequate information and comprehension relationship between disorders required. The dominant clinical manifestations virus infection on respiratory...

Journal: :The Journal of clinical investigation 1979
D R Dantzker J S Bower

We have examined the mechanisms of abnormal gas exchange in seven patients with chronic obliteration of the pulmonary vascular bed secondary to recurrent pulmonary emboli or idiopathic pulmonary hypertension. All of the patients had a widened alveolar-arterial oxygen gradient and four were significantly hypoxemic with arterial partial presssures of oxygen less than 80 torr. Using the technique ...

Journal: :Blood 1960
G RACCUGLIA J V NEEL

With the assistance of Mrs. Ruth T. Davidson and Mrs. Mary Jane Ussery T HE CONGENITAL hemorrhagic diseases characterized by prolonged bleeding time are poorly classified and incompletely understood. The bleeding tendency in these diseases is usually attributed to ( a ) a “defect of the capillary wall,” or ( b ) a “qualitative defect of platelets.” Under the first heading are included those ind...

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