Large soft tissue defects involve significant tissue loss, requiring surgical reconstruction. Autologous flaps are occasionally scant, demand prolonged transfer surgery, and induce donor site morbidity. The present work set out to fabricate an engineered muscle flap bearing its own functional vascular pedicle for repair of a large soft tissue defect in mice. Full-thickness abdominal wall defect...

OBJECTIVE To improve the surgical results of aortic dissection, we used a novel vascular ring connector for anastomosis. METHODS The vascular ring connector is a titanic ring used as a stent in the vascular graft to achieve a quick, blood-sealed, and sutureless anastomosis. From November 2007 to December 2008, 19 consecutive patients (age range 36-77 years; 16 male and 3 female) with aortic d...

conclusions simultaneous arthroscopic acl and pcl reconstructions using hamstring tendon for combined acl and pcl injuries is a clinically effective, safe, time saving and cost-effective procedure with better patient compliance and reproducible for a timely return of motion, strength, and function with favorable outcome. background multiligamentous injuries of knee are a complex problem in orth...

Vascular disease in the patient with diabetes represents a potentially devastating complication. Tri-neuropathy (sensory, motor, and autonomic) often predisposes patients to ulceration and vascular disease leads to delayed healing. Vascular pathology compromises blood flow and oxygen provision, affecting healing, infection, sepsis, amputation, and mortality. Recent research suggests that vascul...

PURPOSE This study was performed to evaluate the feasibility of visualizing soft tissue lesions and vascular structures using contrast-enhanced cone-beam computed tomography (CE-CBCT) after the intravenous administration of a contrast medium in an animal model. MATERIALS AND METHODS CBCT was performed on six rabbits after a contrast medium was administered using an injection dose of 2 mL/kg b...

The goal of the following research project was to perform a three-dimensional reconstruction of selected CDs and associated AVR as they ascend through the IM/OM border, and determine whether AVR in this region coalesce to form giant vascular bundles, or whether they do so in a more dispersed pattern, interacting with components of the interbundle regions. The previously accepted model of vascul...

Rotationplasty is used most often as a function-preserving salvage procedure after resection of sarcomas of the lower extremity; however, it is also used after infection of prosthetic knee joints. Conventional vascular management during rotationplasty is to preserve and coil major vessels, but recently, transection and reanastomosis of the major vessels has been widely performed. However, there...

Therapeutic angiogenesis constitutes an alternative treatment for patients with extensive tissue ischaemia in whom primary vascular reconstruction procedures are not feasible or have previously failed. At present vascular endothelial growth factor (VEGF) has been the most widely used angiogenic factor in experimental and human clinical trials. Early clinical data provide evidence that gene tran...

Abstract Introduction Free flap reconstruction is a routine procedure with more than 99% success rates. Yet, vascular complications may occur leading to failure. Thus, early detection of compromise crucial for salvage. Vascular be detected using Infrared Spectroscopy Tissue Oximetry (NIRS) parameter changes. This method can distinguish changes caused by arterial and venous thrombosis before sur...

BACKGROUND Peripheral arterial disease is a source of morbidity and mortality. Surgical vascular reconstruction is a treatment option but probability of failure and complications are important concerns. In this study, we evaluated outcome of surgical infrainguinal reconstruction and factors affecting graft patency for a period of one year. METHODS In this cohort study, 85 consecutive patients...