Background: Diltiazem is a calcium channel blocker that can prevent absorption by myocytes and decrease the tone of internal anal sphincter. Thus, it be used for treatment fissures; however, its effect on post-hemorrhoidectomy pain unclear. Accordingly, current study aimed to evaluate topical diltiazem pain. Methods: This cohort included 50 candidates hemorrhoidectomy referred Shahid Mohammadi ...

Abstract Background Epidermolysis bullosa (EB) comprises a heterogeneous group of rare genetic diseases associated with skin blistering caused by minimal trauma. A major and common EB subtype, recessive dystrophic (RDEB), is characterized altered wound healing, inflammatory dysbalance fibrotic changes reduced to absent collagen VII. Because its exposed position continued use in daily activities...

Herpes simplex virus-1 (HSV-1) and cytomegalovirus (CMV) are members of the human herpes viridae (HHV) family that can infect give oral manifestations. This case report aims to discuss manifestations HSV-1 CMV infection in a child with cerebral abscess. A 7-year-old boy was referred from Department Pediatrics Oral Medi-cine complaints sore mouth sores, especially when eating, three days ago.Ext...

BACKGROUND Packing after closed reduction of a nasal bone fracture causes inconvenient nasal obstruction in patients. We packed the superior meatus with Vaseline gauze to support the nasal bone, and packed the middle nasal meatus with a Doyle Combo Splint consisting of an airway tube, a silastic sheet, and an expandable sponge to reduce the inconvenience. In addition, we aimed to objectively id...

Le syndrome KID est une anomalie congénitale rare des tissus d'origine ectodermique, caractérisé par une kératite bilatérale progressive accompagnée de néovaisseaux (keratitis), une atteinte cutanée érythro-kératodermique et/ou ichtyosique (ichtyosis) et une surdité de perception sévère (deafness). Nous rapportons le cas d'un jeune garçon de 12 ans, suivi depuis deux ans pour ichtyose, qui cons...

Bioassays for carcinogenicity of various primary processing products (crude oils or tars) and commercial products obtained from Estorian oil shale have been carried out since 1951. The products (undiluted or diluted) were painted twice weekly 50 times on the interscapular area of the skin of random-bred or CC57Br mice. The products processed at high temperatures have a higher carcinogenic activ...

BACKGROUND AND PURPOSE Mexiletine (Mex), an orally effective antiarrhythmic agent used to treat ventricular arrhythmias, has also been found to be effective for myotonia and neuropathic pain. It is extensively metabolized in humans but little information exists about the pharmacodynamic properties of its metabolites. EXPERIMENTAL APPROACH To determine their contribution to the clinical activi...

PURPOSE Evaluation of the healing and persistence of a meshed composite skin graft applied without immunosuppression. METHODS The contraction of wounds grafted with 9:1 split-thickness autograft/1.5:1 allodermal mesh composite skin grafts (auto/allo MCSGs) was investigated. No immunosuppressive agent was applied. Male ACI rats and female Lewis rats reciprocally served as allodermis graft dono...

Circumcision is the surgical removal of the prepucial skin of the penis, some of the complications of traditional circumcision includes; sepsis, genital mutilation, redundant prepuce, gangrene of penis, excessive bleeding, penile amputation or urinary retention, others include loss of penile sensitivity, metal stenosis, and urethrocuteneous fi stula. Among the documented complications we did no...