نتایج جستجو برای: vasogenic brain edema
تعداد نتایج: 510439 فیلتر نتایج به سال:
The mechanisms underlying the rapidly reversible brain swelling described in patients with cerebral malaria (CM) are unknown. Using a 1.5-Tesla (T) magnetic resonance imaging (MRI) scanner, we undertook an observational study in Rourkela, India, of 11 Indian patients hospitalized with CM and increased brain volume. Among the 11 cases, there were 5 adults and 6 children. All patients had reduced...
Background Brain metastases occur in 10-30% of cancer patients with solid extracranial tumors. These tumors are commonly angiogenic and disruption of the blood brain barrier results in edema through the accumulation of extracellular fluid. This vasogenic edema causes injury through raising the intracranial pressure and displacement and damage of brain tissue, resulting in morbidity and mortalit...
Background/introduction The increased interstitial fluid pressure (IFP) from vasogenic edema, which results from a leaky bloodtumor-barrier (BTB), creates a barrier for transvascular drug delivery, particularly larger molecules that are unable to diffuse across and must resort to bulk fluid flow. We have previously used dynamic contrast enhanced-computed tomography (DCE-CT) to quantitatively ev...
BACKGROUND AND PURPOSE Although the term posterior reversible encephalopathy syndrome (PRES) was popularized because of the typical presence of vasogenic edema in the parietal and occipital lobes, other regions of the brain are also frequently affected. We evaluated lesion distribution with CT and MR in a large cohort of patients who experienced PRES to comprehensively assess the imaging patter...
BACKGROUND AND PURPOSE With the advent of thrombolytic therapy for acute stroke, reperfusion-associated mechanisms of tissue injury have assumed greater importance. In this experimental study, we used several MRI techniques to monitor the dynamics of secondary ischemic damage, blood-brain barrier (BBB) disturbances, and the development of vasogenic edema during the reperfusion phase after focal...
BACKGROUND AND PURPOSE Blood-brain barrier disruption and consequent vasogenic edema formation codetermine the clinical course of intracerebral hemorrhage (ICH). This study examined the effect of PHA-543613, a novel α7 nicotinic acetylcholine receptor agonist, on blood-brain barrier preservation after ICH. METHODS Male CD-1 mice, subjected to intrastriatal blood infusion, received PHA-543613 ...
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