60 cervical Chlamydia trachomatis infections identified by antigen detection from 51 prostitute women in Nairobi, Kenya were evaluated for sequence polymorphism in the major outer membrane protein (omp1) gene. DNA from clinical specimens was amplified by the polymerase chain reaction and cycle sequenced through variable domains (VD) 1, 2, and 4.37 (63%) samples had variant VD sequences, 19 (32%...

The population pharmacokinetics on tazobactam/piperacillin (TAZ/PIPC; 1:8, 4.5 g x 3) was analyzed in Japanese patients with community-acquired pneumonia using the Nonlinear Mixed Effect Model version VI. Analysis by the one-compartment model yielded the following results for PIPC: total clearance (CL) = 8.22+(Ccr-71.4) x 0.0561 (L/hr), distribution volume (Vd) = 13.7 (L). The pharmacokinetic p...

OBJECTIVE To evaluate nulliparous breech delivery so as to determine prognostic factors for an unsafe vaginal delivery (VD). METHODS This retrospective and descriptive study was carried out in the University Teaching Hospital Yaoundé-Cameroon, from January 1, 2005 to December 31, 2009. Files of 126 women with singletons in breech presentation and normal fetal heart beats at a gestational age ...

BACKGROUND The aim of this study was to determine the effect of gestational age on pharmacokinetics of ranitidine in newborns with gastroesophageal reflux. METHODS A prospective, descriptive and pharmacokinetic study was carried out in 30 pre-term and 20 full-term babies. 3 mg/kg of ranitidine was administered intravenously to all the babies and at 0.25, 0.5, 1, 2, 4, and 8 h following the ad...

Propranolol plasma levels and kinetic disposition may be altered by hypothermic cardiopulmonary bypass (CPB-H). We investigated the potential influence of obesity on propranolol pharmacokinetics in patients undergoing coronary artery bypass grafting employing CPB-H. Fifteen patients, receiving propranolol perorally pre(1040 mg, 2-3 times a day) and post-operatively (10 mg, once a day) were dist...

Both epidemiologic and laboratory studies have shown the chemopreventive effects of 1a,25-dihydroxyvitamin D3 (1,25-VD) in tumorigenesis. However, understanding of the molecular mechanism by which 1,25-VD prevents tumorigenesis remains incomplete. In this study, we used an established mouse model of chemical carcinogenesis to investigate how 1,25-VD prevents malignant transformation. In this mo...

The effects of pulsed electric field (PEF) treatment and preliminary vacuum drying (VD) on freezing assisted processes for the potato tissue were studied. PEF was done at 600 V/cm using protocol to insure high level disintegration. VD sub-atmospheric pressure p = 0.30 bar. Such conditions allowed relatively fast dehydration accelerated by low or moderate temperatures inside sample (<50 °C). Imp...

BACKGROUND In Taiwan, next to Alsheimer's, vascular dementia (VD) is the second leading cause of dementia in the elderly. Few studies have examined cardiovascular risk factors and their association with VD in Taiwan. METHODS This is a case-control study using a sampling of subjects from the outpatient memory clinics of two hospitals. Identified cases were those patients diagnosed with VD base...

The dissociable neural subsystems theory proposes that left-hemisphere (LH) performance is dominated by a viewpoint-invariant (VI) recognition subsystem, whereas right-hemisphere (RH) performance is dominated by a viewpoint-dependent (VD) subsystem (Marsolek, 1999). Studies supporting this theory have used familiar objects and, therefore, may have been confounded by characteristics beyond perce...