background: there is some evidence indicating improvement in myocardial performance after atrial septal defect closure, either device closure or surgical, but ventricular dyssynchrony has not been evaluated before and after surgical closure. the aim of this study was to evaluate ventricular mechanical dyssynchrony in patients with atrial septal defect before and after surgical closure. methods:...

An increase of cardiac late sodium current (INa.L) is arrhythmogenic in atrial and ventricular tissues, but the densities of INa.L and thus the potential relative contributions of this current to sodium ion (Na(+)) influx and arrhythmogenesis in atria and ventricles are unclear. In this study, whole-cell and cell-attached patch-clamp techniques were used to measure INa.L in rabbit left atrial a...

propafenone hci (p), is a relatively new class ic antiarrhythmic agent. it has been reported to be superior to conventional antiarrhythmics in the control of supraventricular, ventricular and wpw associated tachyarrhythmias. it has been also shown to be well tolerated. in our study protocol, which extends over 2~ years period , we used (p) in 87 patients for management of various types of cardi...

Gap junctions are composed of connexin (Cx) proteins, which mediate intercellular communication. Cx43 is the dominant Cx in ventricular myocardium, and Cx45 is present in trace amounts. Cx43 immunosignal has been associated with cell-to-cell coupling and electrical propagation, but no studies have directly correlated Cx43 immunosignal to electrical cell-to-cell conductance, g(j), in ventricular...

A B S T R A C TIntroduction: Because of more exposure to mercury compounds, the prenatal and postnatal neurotoxic effects of mercury compounds have gained more attention in last decade. The aim of this study was to investigate the effects of mercuric chloride intoxication on spinal cord development during prenatal period. Methods: 36 adult Sprague-dawley rats after observing vaginal mating plaq...

Six hundred 1-d-old male broilers (Ross 308) were assigned to four experimental groups; each was composed of 5 floor pen replications of 30 birds including control (no enalapril), 15, 30 and 60 ppm enalapril in the drinking water. From d 21 to 49, all the chicks were exposed to low ambient temperature to induce ascites. Mortalities were inspected to determine the cause of death and diagnose of ...

performance of heart has substantial role in breaking records of sports. achieving to optimal performance of endurance training builds upon the consistency in several parts of body specially heart. type, intensity, term training programs is determining components of providing structural consistency and performance of heart especially in left ventricular. aim of this research was comparing struc...

takotsubo cardiomypathy is a very rare cardiovascular syndrome leading to myocardial infarction and left ventricular dysfunction in the absence of a detectable coronary artery lesion. it is accepted as reversible left ventricular asynergy occuring typically after an intrinsic adrenergic hyperstimulation. in this report we present takotsubo cardiomyopathy in a 75-year-old patient with multiple a...