In Arabidopsis, variant in methylation (VIM) proteins are required for the maintenance of DNA methylation in the CpG dinucleotide context. VIM1 acts as a cofactor of DNA methyltransferase 1 (MET1), although the mechanism for this co-regulation remains unclear. In this study, we used RNA-seq analysis to profile the transcriptomes of vim1, vim1 vim2 vim3, and met1 null mutants. Consistent with pr...

Psoriasis is similar to endpoints of epithelial-mesenchymal transition (EMT), a process of epithelial cells transformed into fibroblast-like cells. The molecular epithelial and mesenchymal markers were analysed in psoriatic keratinocytes. No obvious alteration of epithelial markers E-cadherin (E-cad), keratin 10 (K10), K14 and K16 was detected in psoriatic keratinocytes. However, significantly ...

    In this paper, a variational iteration method (VIM), which is a well-known method for solving nonlinear equations, has been employed to solve an inverse parabolic partial differential equation. Inverse problems in partial differential equations can be used to model many real problems in engineering and other physical sciences. The VIM is to construct correction functional using general Lagr...

A recent study has proved that unilateral deep brain stimulation (DBS) of the subthalamic nucleus has bilateral effects. However, it is still unclear whether unilateral ventral intermediate thalamic nucleus (Vim) DBS exerts exclusively contralateral or bilateral effects on tremor. Previous studies demonstrated a clinically irrelevant improvement on the nontarget side after thalamic stimulator i...

In this paper, a vaccination susceptible exposed infected recovered (VSEIR) model f o r tuberculosis in North Sumatera is discussed. The VSEIR model is formed by a system of nonlinear differential equations. The approximate solution of this model is obtained by using the step variational iteration method (SVIM) and variational iteration method (VIM). VIM used the general Lagrange multiplier in ...

Penggunaan Styrofoam dan plastik LDPE sebagai aditif aspal keras untuk campuran porus diharapkan bisa menjadi solusi mengatasi permasalahan limbah yang sulit terurai. Tujuan dari penelitian ini adalah mengetahui nilai karakteristik Marshall pada dengan variasi kadar 8%, 10%, 12%, 14%, perbandingan optimum 14% porus. Karakteristik meliputi stabilitas, Flow, VIM, MQ. Dapat disimpulkan mendapatkan...

PURPOSE The variational Bayesian independent component analysis-mixture model (VIM), an unsupervised machine-learning classifier, was used to automatically separate Matrix Frequency Doubling Technology (FDT) perimetry data into clusters of healthy and glaucomatous eyes, and to identify axes representing statistically independent patterns of defect in the glaucoma clusters. METHODS FDT measure...

Objective: Ras-related C3 botulinum toxin substrate1(Rac1) and epithelial mesenchymal transition (EMT) are key therapeutic targets in cancer. We investigated the clinical significance of Rac1 and markers of EMT expression in non-small cell lung cancer (NSCLC), and their possible correlation with EMT phenotype. Methods: Immunohistochemistry was used to assess the expression of Rac1, Snail1, Twis...

BACKGROUND Multidrug-resistant Pseudomonas aeruginosa is a serious challenge for antimicrobial therapy of nosocomial infections, as it possesses several mechanisms of antimicrobial resistance. In Central Greece, a sudden increase of infections caused by carbapenem-resistant P. aeruginosa was observed during 2011, indicating the need for further analysis. METHODS Five-hundred and sixty-eight P...