نتایج جستجو برای: viral gene delivery

تعداد نتایج: 1439069  

Journal: :Chemical communications 2011
Ruijun Xing Gang Liu Qimeng Quan Ashwinkumar Bhirde Guofeng Zhang Albert Jin L Henry Bryant Angela Zhang Amy Liang Henry S Eden Yanglong Hou Xiaoyuan Chen

A non-viral gene delivery nanovehicle based on Alkyl-PEI2k capped MnO nanoclusters was synthesized via a simple, facile method and used for efficient siRNA delivery and magnetic resonance imaging.

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2012
Xiaohong Jiang Hao Gong Yuan-Chuan Chen Gia-Phong Vu Phong Trang Chen-Yu Zhang Sangwei Lu Fenyong Liu

Ribonuclease P complexed with external guide sequence (EGS) bound to mRNA represents a unique nucleic acid-based gene interference approach for modulation of gene expression. Compared with other strategies, such as RNA interference, the EGS-based technology is unique because a custom-designed EGS molecule can hybridize with any mRNA and recruit intracellular ribonuclease P for specific degradat...

2007
S. Steven Floyd David K. Booth Johnny Huard

Duchenne Muscular Dystrophy (DMD) is an inherited muscle disease that is characterized by a lack of dystrophin expression in the membrane cytoskeleton of muscle fibers. This lack of dystrophin is responsible for muscle fiber necrosis which leads to the muscle atrophy and progressive muscle weakness, characteristic of the DMD pathology. Myoblast transplantation and gene therapy based on viral ve...

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