AIM To report the early vitreous involvement in a rare familial amyloidotic polyneuropathy (FAP) mutation and associated vitreous vascular endothelial growth factor (VEGF) levels. DESIGN Observational case series. METHODS Review of clinical, pathological, photographic, and angiographic records of two FAP siblings with severe vitreous involvement. Laboratory ELISA analysis of vitreous sample...

PURPOSE To compare the hemostatic effect of sulfur hexafluoride 20% (SF6 20%) with lactated Ringer's solution for prevention of early postoperative vitreous hemorrhage following diabetic vitrectomy. METHODS In a prospective randomized clinical trial, 50 eyes undergoing diabetic vitrectomy were divided into two groups. At the conclusion of surgery, in one group the vitreous cavity was filled w...

Candida albicans is the most common pathogen causing intraocular fungal infection. Postpartum endogenous Candida endophthalmitis, however, is extremely rare. We report the case of a 33-year-old postpartum woman who presented with a 5-day history of decreased vision and had a positive blood culture for C. albicans. Fundus examination showed vitreous haze and multiple pre-retinal whitish lesions ...

OBJECTIVE To evaluate the diagnostic value of polymerase chain reaction (PCR) performed on vitreous, aqueous and conjunctiva for the detection of cytomegalovirus in AIDS patients with a clinical diagnosis of cytomegalovirus retinitis. MATERIAL AND METHOD PCR-based assay was used to detect cytomegalovirus DNA in vitreous, aqueous and conjunctival samples from 24 patients with the acquired immu...

Vitreoretinal surgery has advanced in numerous directions during recent years. The removal of the vitreous body is one of the main characteristics of this surgical procedure. Several molecules have been tested in the past to fill the vitreous cavity and to mimic its functions. We here review the currently available vitreous substitutes, focusing on their molecular properties and functions, toge...

CASE REPORT A 43 year-old female presented with decreased visual acuity in the right eye. «Snowball-like» retinal lesions were found in both eyes on examination. Due to a lack of improvement with intravitreal antifungal empirical treatment, vitreous culture was performed and Candida glabrata was isolated. The patient then received intravitreal amphotericin B, as well as systemic treatment with ...

Vitreous hemorrhage is the most frequent finding in ocular trauma. In cases with obscured fundus visualization associated pathologies (retinal tear, choroidal detachment, intraocular foreign body, retinal etc.) should be evaluated by ultrasonography and vitreous motility monitored even if retina attached. A decrease points to development of proliferative vitreoretinopathy requires early vitrect...

background: the diagnosis of ocular toxoplasmosis is mainly based on clinical features. however, ocular fluid testing by pcr may be very helpful for approval or rejection of this etiology. in this study, we utilized a nested-pcr technique, targeting the b1 partial sequence to analyze the aqueous and vitreous samples for evaluating the presence of the toxoplasma dna. methods: fifty aqueous or vi...