The graft versus host reaction (GVHR), which results from the injection of parental strain spleen cells beneath the kidney capsule of F(1) hybrid rats, is transferable during its developmental phase into F(1) hybrid hosts isogeneic with the primary host, but not into secondary hosts of the parental (donor) strain. Furthermore, the GVHR propagates but rarely in secondary hybrid hosts which are a...

An allogeneic transplant recipient developed severe graft versus host disease (GvHD) 48 days after transplantation that was concomitant with a cytomegalovirus (CMV) viraemia, from which she subsequently died. CMV infection was detected in blood by the polymerase chain reaction and later in tissue by immunohistochemical techniques. CMV should be considered in patients in whom GvHD does not respo...

Introduction: Evaluation of the cerebrospinal fluid (CSF) white blood cell (WBC) count and glucose and protein concentrations is used to assess the probability of the presence of central nervous system (CNS) infection. Although normal values are well established for CSF cell counts and protein and glucose contents in children and adults, this is not the case for neonates. The purpose of this st...

Unfortunately, the vast majority (90%) of new anticancer agents designed in the laboratory never make it into routine clinical use. The hypothesis of this lecture is that many new agents fail in the clinic because the appropriate clinical trial(s) that could exploit the attributes of the new agent are not performed. An appreciation that both bench and clinical investigations are difficult endea...

This study aimed to investigate the surface roughness and gloss of composite resins after using two polishing systems and toothbrushing. Six composite resins (Durafill VS, Filtek Z250, Filtek Z350 XT, Kalore, Venus Diamond, and Venus Pearl) were evaluated after polishing with two polishing systems (Sof-Lex, Venus Supra) and after toothbrushing up to 40,000 cycles. Surface roughness (Ra) and glo...

Of these three books which deal with disease of the throat and nose, the first one no longer needs any introduction. We notice, however, that its author has changed the title of his work, and the additional pages on rhinology render the book distinctly more valuable than the previous editions. Mr. Lennox Browne evidently does not believe in specialising too narrowly, because he considers that t...

The present studies extend our previous efforts to understand the immunological basis of specifically induced graft-versus-host (GVH) resistance in F1 hybrid rats. Immunization of F1 rats with alloreactive T-cell populations of parental strain origin induces a host-mediated T-cell response which is specific for anti-major hostocompatibility complex receptors on parental T cells. This protective...

tributed equally to this study. Study concept and design: C. Lim and S.-L. Lim. Acquisition of data: C. Lim and S.-L. Lim. Analysis and interpretation of data: C. Lim and S.-L. Lim. Drafting of the manuscript: C. Lim and S.-L. Lim. Critical revision of the manuscript for important intellectual content: C. Lim and S.-L. Lim. Administrative, technical, and material support: C. Lim and S.-L. Lim. ...

Three automatic alignment systems are compared in their adequacy to account for the vowel schwa as compared to a manual transcription obtained from two judges. Error rates and types are analysed, as well as the linguistic factors involved. The type of surrounding consonants and the duration of schwa influence the decisions of the three systems. Moreover, the systems behave differently, dependin...