Short tandem repeat (STR) loci in the human genome can be used for individual identification (1). Simultaneous PCR-amplification and size determination at several STR loci is desirable in order to: (i) increase the information gained when only very small amounts of template DNA are available, (ii) maximise throughput of samples and (iii) minimise costs. One means of increasing the number of loc...

In a number of applications there is a need to determine the most likely pedigree for a group of persons based on genetic markers. Adequate models are needed to reach this goal. The markers used to perform the statistical calculations can be linked and there may also be linkage disequilibrium (LD) in the population. The purpose of this paper is to present a graphical Bayesian Network framework ...

Context. One of the main goals of the COROT mission is to get precise photometric observations of selected bright stars in order to allow the modelling of their interior through asteroseismology. However, in order to interpret the asteroseismological data, the effective temperature, surface gravity, and chemical composition of the stars must be known with sufficient accuracy. Aims. To carry out...

Due to the miscegenation of the Brazilian population, the central region of Brazil was colonized by internal migration of individuals from different origins, who contributed to the genetic diversity existing in this population. The purpose of this study was to estimate population parameters based on the allele frequencies for 15 polymorphic autosomal short-tandem repeat (STR) loci present in th...

189 samples from 3 different U.S. sample groups Caucasian (74), African American (71) and Hispanic (44) were typed for 70 autosomal genetic markers. These 70 markers are bi-allelic (C/T) short nucleotide polymorphisms (SNPs). For each sample, the 70 SNP markers were typed in 11 unique 6-plexes and a single 4-plex PCR. A total of 10 of the 210 tests (70 loci x 3 populations) for Hardy-Weinberg e...

Empirical tests of association between Y chromosome and autosomal markers are presented and a theoretical framework for determining a joint match probability is recommended. Statistical analyses of association were performed in 16 US populations between the autosomal genotypes from loci CSF1PO, FGA, THO1, TPOX, vWA, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S512, D21S11 and Y chrom...