The digitization of manufacturing processes has led to an increase in the availability process data, which enabled use data-driven models predict outcomes these processes. Data-driven are instantaneous simulate and can provide real-time predictions but lack any governing physics within their framework. When data deviates from original conditions, may not agree with physical boundaries. In such ...

Current research has been done to develop statistically and optimized immediate release tablets for eslicarbazepine. Nineteen formulations of eslicarbazepine acetate are prepared by wet granulation. The three-dimensional Box-Behnken design at three levels (33) was developed study how selected independent variables affect dependent responses. After the initial test, items were as follows; polyvi...

Introduction. Herbal medicines are increasingly being used in the treatment of various diseases. Significant number resources, high-level availability and possibility cultivation have provided high prospects plant raw materials development new herbal medicines. Primula denticulate Smith. is one most interesting medicinal source modern medicine pharmacy with wide spectrum pharmacotherapeutic act...

Starch is a carbohydrate that can be used as binder in pharmaceutical preparations. Paracetamol has poor flowability and compactibility with its crystalline form, it necessary to make granules by wet granulation method starch binder. This study banana peel waste (Musa paradisiaca) source of starch. Three granule formulations (F1, F2, F3) were prepared using the concentrations 5% (F1), 8% (F2), ...

The present work was carried out to formulate and evaluate immediate release tablets of Inosine Acedoben Dimepranol (IAD). Tablets were prepared by wet granulation process overcome the poor compression properties IAD powder produce high-dose tablets. Various type binders disintegrants like Povidone K-30, K-25, wheat starch, mannitol used prepare some series Granules evaluated for pre-compressio...

The metal-organic frameworks (MOFs) MIL-100(Fe), Cu-BTC and CPO-27(Ni) were synthesised in 1 kg batches. The materials were then formed in two different industrially relevant ways. Firstly, dry granulation was used to produce pellets which were sieved to give material with a 300-1000 μm size, and the fines were subsequently recycled to mimic a large scale industrial process. Secondly, wet granu...

Acute compartment syndrome (ACS) is a serious complication of lower-extremity trauma caused by accidents or post-procedure complications. ACS is characterized by increased pressure within the compartment, resulting in reduced blood flow, tissue hypoxia, and tissue necrosis. Fasciotomies to relieve pressure and debridement of necrotic tissue comprise primary treatment. My purpose is to present i...