the aim of this study was to assess the possible association between genetic polymorphisms of the glutathione s-transferase (gst) gene family and the risk of the development of metabolic syndrome (ms) in zoroastrian females in yazd, iran.in this case-control study, gstm1, t1, and p1 polymorphisms were genotyped in 51 randomly selected ms patients and 50 randomly selected healthy controls on feb...

background: major histocompatibility complex (mhc) in chicken has profound influence on resistance/susceptibility to disease, and production and reproduction traits. microsatellite marker lei0258 is a genetic indicator for mhc haplotypes. recognizing diversity of mhc haplotypes in selectively bred populations will be helpful for selecting population resistant to disease and development of effec...

cystic fibrosis (cf) is a life-limiting autosomal recessive disorder affecting principally respiratory and digestive system . it is caused by cystic fibrosis transmembrane conductance regulator (cftr) gene mutation. the aim of this study was to determine the extent of repeat numbers and the degree of heterozygosity for c.3499+200ta(7_56) and d7s523 located in intron 17b and 1 cm proximal to the...

The allelofund of Ayrshire cattle the Komi Republic (n=340) and Kirov region (n=32) was evaluated using microsatellite DNA markers. It found that in studied populations, TGLA227 locus most polymorphic – 9 alleles, BM1824 TGLA126 loci had least alleles (3-4). allele 214 INRA23 (q=0.7387) with highest frequency Republic, 115 (q=0.7083) among animals region. average number per samples slightly hig...

Background: Different studies have demonstrated that a small proportion of healthy individuals receiving the hepatitis B (HB) vaccine do not produce protective levels of anti-HB antibody, a phenomenon which could be linked to certain human leukocyte an-tigen (HLA) class-II alleles or haplotypes. Objectives: The present study was under-taken to determine the frequency of HLA class-II alleles in ...

Abstract Robinia pseudoacacia is an important afforestation tree introduced to China in 1878. In the present study, we examined genetic diversity among 687 strains representing four improved varieties and two secondary provenances, comprising 641 clones 46 seedlings. Ninety-one simple sequence repeats (SSRs) were selected through segregation analysis polymorphism characterization, all sampled i...

A polymorphism in the promoter of human NRAMP1 encodes a Z-DNA forming dinucleotide repeat with four alleles: (1) t(gt)5ac(gt)5ac(gt)11g; (2) t(gt)5ac(gt)5 ac(gt)10g; (3) t(gt)5ac(gt) ac(gt)9g; and (4) t(gt)5ac(gt)9g. Alleles 1 and 4 are rare (gene frequencies approximately 0.001); alleles 2 and 3 occur at gene frequencies approximately 0.20-0.25 and approximately 0.75-0.80, respectively. Here,...