The diagnosis of enteric fever currently depends upon the isolation of Salmonella from a patient, most commonly by blood culture. This facility is not available in many areas where the disease is endemic. Serodiagnosis depends upon the 100-year-old Widal test, and other serological diagnostic tools have limitations because of their low sensitivity and/or specificity. The most promising recently...

Clinical features, laboratory findings, and complications of typhoid fever were correlated with sex through a retrospective case note review of 102 hospitalized culture-positive patients in Durban, South Africa. Intestinal perforation (P = 0.04), occult blood losses in stools (P = 0.04), and a mild reticulocytosis in the absence of hemolysis (P = 0.02) occurred more frequently in males than in ...

We report a case of typhoid fever with an unusual presentation: prolonged fever with cutaneous vasculitis, pleural effusion and splenic abscess. The diagnosis was made upon Widal serology, and after ruling out other causes of leukocytoclastic vasculitis. The outcome was favourable with antibiotics alone and without surgery.This is the second case of cutaneous leukocytoclastic vasculitis associa...

G La Ruche ([email protected])1, A Goubard2, B Berçot3, E Cambau3, C Semaille1, P Sednaoui2 1. French Institute for Public Heath Surveillance, Department of infectious diseases, Saint-Maurice, France 2. Institut Alfred Fournier, National Reference Laboratory for gonorrhoea, Paris, France 3. Laboratory of Bacteriology, Virology and Hygiene, Saint-Louis/Lariboisière/Fernand Widal hospitals,...

Cerveau et de L’Œil, Groupe Hospitalier Lariboisière – Fernand Widal, Paris, France ; 5 INSERM UMR_S 740, Université Paris Diderot, Sorbonne Paris Cité, Paris 6 Service de Neurologie, CHU de Limoges, Hôpital Dupuytren, Limoges, France; 7 Service de Cardiologie, CHU de Limoges, Hôpital Dupuytren, Limoges, France; 8 Unité Mixte de Recherche en Santé (UMR_S956), Université Pierre & Marie Curie (UP...

Salmonella typhi splenic abscesses are a very rare complication of typhoid fever. Splenectomy is the standard surgical treatment for these lesions. But these days, with improvements in imaging techniques, percutaneous drainage of splenic abscesses has been demonstrated to be one of the alternative treatment in selected cases. We report the case of a 7 year-old male, who presented with Salmonell...

The antibody response of patients with various infections has been utilized as an aid to diagnosis since the early days of scientific microbiology, as exemplified by the Widal, Wassermann, and Weil-Felix tests. A variety of serologic techniques have been used to this end. In our laboratories we have studied the antibody response by means of the passive bacterial hemagglutination test on patient...