background: cutaneous leishmaniasis (cl) is a parasitic disease in most parts of iran, especially in the isfahan province. the most common form of cl is a self-healing lesion but in rare situations, infection might develop to non-healing forms. clinical symptoms and treatment process might be influenced by several agents such as host immune response and parasite strains. in this study, the isol...

introduction: a traumatic arteriovenous fistula (avf) after repetitive blunt trauma has not been described previously. in a 34-year-old male, the first reported case of such an injury after repetitive blunt trauma is described. case presentation: a 34-year-old gentleman presented with a non-healing ulcer near his medial malleolus. a bone scan was performed and then treated for presumed osteomye...

background wound healing is a complicated and integrated process. researches have indicated the wound healing effects of calcium channel blockers in animal models in recent years. objectives the aim of this study was to evaluate the wound-healing activity of amlodipine as a calcium channel blocker and combination of amlodipine with phenytoin on excisional cutaneous wound models in rabbit. mater...

Introduction: Mummy was used in traditional medicine as a remedy for inflammation, articular injuries, rheumatism, bone fractures, wounds, and back pains. In a previous research, the healing effects of mummy on rabbit’s tibial fracture were studied and the results approved its efficacy. Considering some natives’ claim and suggestions of traditional medicine in regard to the effectiveness of mum...

PURPOSE Intracellular reactive oxygen species have been reported to associate with growth factor and integrin signalings in promoting cell adhesion in many cell types. This study is to explore if exogenous H(2)O(2) at low levels can be beneficial to cell adhesion, migration, and wound healing. METHODS Primary rabbit corneal epithelial cells treated with 0-70 μM H(2)O(2) were tested for viabil...

aloe littoralis baker (asphodelaceae family) is a well known plant in southern parts of iran. because of its use in iranian traditional medicine as a wound-healing agent, the present study was carried out to investigate anti-inflammatory and wound healing activities of this plant in wistar rats. a. littoralis raw mucilaginous gel (alrmg) and also two gel formulations prepared from the raw mucil...

Wound healing is initiated and progressed by complex integrated process of cellular, physiologic, and biochemical events, such as inflammation, cell migration and proliferation. Interleukin 6 (IL-6) is a multifunctional cytokine, and it could regulate the inflammatory response of wound healing process in a timely manner. Hyaluronic acid (HA) is an essential component of the extracellular matrix...

Skin wound healing is a complex process requiring the coordinated, temporal orchestration of numerous cell types and biological processes to regenerate damaged tissue. Previous work has demonstrated that a functional β-adrenergic receptor autocrine/paracrine network exists in skin, but the role of β2-adrenergic receptor (β2AR) in wound healing is unknown. A range of in vitro (single-cell migrat...