A number of cyclic peptides including [FR]4, [FK]4, [WR]4, [CR]4, [AK]4, and [WK]n (n = 3-5) containing L-amino acids were produced using solid-phase peptide synthesis. We hypothesized that an optimal balance of hydrophobicity and charge could generate self-assembled nanostructures in aqueous solution by intramolecular and/or intermolecular interactions. Among all the designed peptides, [WR]n (...

Wolf-Rayet (WR) galaxies provide detailed information on massive star populations in starbursts and thereby represent ideal objects to determine accurate ages for young systems, to measure the burst duration, and to probe the upper end of the IMF. WR galaxies play also a particular role in a variety of studies on star formation in Seyfert2/LINERS, dust production and local chemical enrichment, ...

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Through an in vivo and in vitro analysis of the absorption kinetics of S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721) in the normal tissues and solid tumors of mice, rats, and rabbits, it has been demonstrated that normal tissues actively concentrate WR-2721 against a concentration gradient, whereas solid tumors passively absorb it, or, if active concentration of WR-2721 is present...

INTRODUCTION/PURPOSE This study's purpose was to develop and employ a technique to determine the fastest masters marathon world records (WR), ages 35-79 years, adjusted for age (WRadj). METHODS From single-age WR data, a best-fit polynomial curve (WRpred1) was developed for the larger age range of 29-80 years for women and 30-80 years for men to improve curve stability in the 35-79 years rang...

Wild rice (WR) is a very nutritious grain that has been used to treat diabetes in Chinese medicinal practice. City diet (CD) is based on the diet consumed by Asian area residents in modern society, which is rich in saturated fats, cholesterol and carbohydrates. The present study was aimed at evaluating the effects of replacing white rice and processed wheat starch of CD with WR as the chief sou...