نتایج جستجو برای: xenograft model

تعداد نتایج: 2117815  

2013
Fang Hou Yuemeng Dai James Y Suen Chunyang Fan Ali G Saad Gresham T Richter

BACKGROUND Arteriovenous malformations (AVMs) are a type of high-flow vascular malformations that most commonly occurs in the head and neck. They are present at birth but are usually clinically asymptomatic until later in life. The pathogenesis of AVMs remains unclear and therapeutic approaches to AVMs are unsatisfied. In order to provide a tool for studying the pathogenesis and therapies of th...

Journal: :Cancer 2007
Brian T Ragel Randy L Jensen David L Gillespie Stephen M Prescott William T Couldwell

BACKGROUND Treatments for recurrent meningiomas are limited. We previously demonstrated universal expression of COX-2 in meningiomas and dose-dependent growth inhibition in vitro with celecoxib, a COX-2 inhibitor. We therefore tested the effects of celecoxib on meningioma growth in a mouse xenograft model. METHODS Meningioma cell lines (IOMM-Lee, CH157-MN, WHO grade I primary cultured tumor) ...

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