نتایج جستجو برای: xrcc1 arg399gln

تعداد نتایج: 1145  

Journal: :Anticancer research 2011
Tomomitsu Tahara Tomoyuki Shibata Masakatsu Nakamura Hiromi Yamashita Daisuke Yoshioka Masaaki Okubo Joh Yonemura Yoshio Kamiya Takamitsu Ishizuka Yoshihito Nakagawa Mitsuo Nagasaka Masami Iwata Ichiro Hirata Tomiyasu Arisawa

BACKGROUND Genetic factors related to DNA repair or xenobiotic pathways might confer different degrees of susceptibility to Helicobacter pylori (H. pylori)-related gastric carcinogenesis. The association between XRCC1 Arg399Gln, and Arg194Trp, GSTP1 Ile104Val, and GSTT1, GSTM1 null polymorphisms with gastric intestinal metaplasia, severity of histological gastritis, and peptic ulcer diseases we...

2013
Yi Bao Lei Jiang Jue-Yu Zhou Jun-Jie Zou Jiao-Yang Zheng Xiang-Fang Chen Zhi-Min Liu Yong-Quan Shi

BACKGROUND Previous studies investigating the association between X-ray repair cross-complementing group 1 (XRCC1) polymorphisms and thyroid cancer risk have yielded inconsistent results. This meta-analysis was performed to derive a more precise estimation of the relationship between three XRCC1 polymorphisms and thyroid cancer risk. METHODS/PRINCIPAL FINDINGS PubMed and EMBASE database were ...

Journal: :Genetics and molecular research : GMR 2008
R M Dufloth A Arruda J K R Heinrich F Schmitt L C Zeferino

The association of tumor differentiation and estrogen receptor expression with the prognosis of breast cancer has been well established. Nevertheless, little is yet reported about the association of morphological characteristics of the tumor, estrogen receptor status and polymorphisms in low penetrance genes. The aim of the present study was to investigate a possible association between DNA rep...

Journal: :International journal of clinical and experimental medicine 2015
Ai-Qin Gu Wei-Ming Wang Wen-Yi Chen Chun-Lei Shi Jian-Hong Lu Jun-Qing Han

OBJECTIVE To evaluate the correlation between genetic polymorphisms in x-ray repair cross complementing group 1 (XRCC1) and sensitivity to platinum-based chemotherapy drugs in patients with non-small cell lung cancer. METHODS Reports published before June 2014 were retrieved from the following databases: China Biology Medicine (CBM), China Academic Journal Full-Text Database (CNKI), China Sci...

Journal: :Carcinogenesis 2003
Wei-Min Gao Marjorie Romkes Richard D Day Jill M Siegfried James D Luketich Hussam H Mady Mona F Melhem Phouthone Keohavong

Lung cancer, a disease related mostly to tobacco smoke exposure and a leading cause of cancer-related death in industrialized countries, is frequently associated with mutations in the p53 tumor suppressor gene. Genetic differences resulting in inter-individual variation in DNA repair capacity may in part account for susceptibility of a cell to genotoxic agents leading to somatic mutations, incl...

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