Author’s Note: Special Thanks for their support to Emily Morganti and Heather Logas of Telltale Games; Becky Waxman, Jan Christoe and Marita Robinson of GameBoomers; Stefaan de Keersmaeker, a.k.a. “Father,” of The Older Gamers; Jen at FourFatChicks.com; Cindy at MysteryManor.com; Tami at Spyglassguides.com; Mina at grrlgamer.com; the team at Seasoned Gamers; Chris Morris; Betsy Book; and all th...

Let W= W(xx,...,Xj)bc any word in thej free generators xx,...,Xj, and suppose that W cannot be expressed in the form W = Vk for V a word and for k an integer with \k\¥" 1. We ask whether the equation f=W has a solution (xx>... ,Xj) = (a,,... ,Oj) €E GJ whenever G is an infinite symmetric group and/is an element in G. We establish an affirmative answer in the case that W(x, y) = xmy" for m and n...

OBJECTIVE The purpose of this study was to investigate the association between two genetic polymorphisms (PvuII and XbaI restriction fragment length polymorphisms, RFLPs) of the estrogen receptor-alpha (ER1) gene and the quantitative ultrasound (QUS) parameters at the calcaneus. SUBJECTS AND METHODS Two hundred and sixty-six Korean vegetarian men, mean age 50.9+/-12.0 years (range 26-80), wer...

Medaka, Oryzias latipes, has a firm XX-XY sex-determining system with the sex-determining gene, DMY, on the Y chromosome. However, previous studies have suggested that high water temperature might affect sex determination in Medaka. In the present study, the influence of high water temperature on sex reversal was examined. Fertilized eggs of two inbred strains of Medaka were developed at high w...

Optical lattice formed by counter propagating laser beams provides us a new platform to study condensed matter physics. Cold atoms moving in an optical lattice could be described by BoseHubbard Model. By controlling laser intensity, we could change interaction and tunneling strength at will. Thus, different quantum phases could occur in optical lattice. In this review, I will give an overview o...

We report on the diamagnetic responses of different exciton complexes in single InAs/GaAs self-assembled quantum dots (QDs) and quantum rings (QRs). For QDs, the imbalanced magnetic responses of inter-particle Coulomb interactions play a crucial role in the diamagnetic shifts of excitons (X), biexcitons (XX), and positive trions (X-). For negative trions (X-) in QDs, anomalous magnetic response...

Differentiation of the bipotential gonad into testis is initiated by the Y chromosome-linked gene SRY (Sex-determining Region Y) through upregulation of its autosomal direct target gene SOX9 (Sry-related HMG box-containing gene 9). Sequence and chromosome homology studies have shown that SRY most probably evolved from SOX3, which in humans is located at Xq27.1. Mutations causing SOX3 loss-of-fu...

Although the disorder of sex development in dogs with female karyotype (XX DSD) is quite common, its molecular basis is still unclear. Among mutations underlying XX DSD in mammals are duplication of a long sequence upstream of the SOX9 gene (RevSex) and duplication of the SOX9 gene (also observed in dogs). We performed a comparative analysis of 16 XX DSD and 30 control female dogs, using FISH a...

OBJECTIVE To develop a mathematical model for more precise estimation of the incidence of chromosomal abnormalities and the sex ratio among spontaneous abortions masked by maternal cell contamination. DESIGN Retrospective analysis. SETTING Academic medical center. PATIENT(S) One hundred twelve samples of spontaneous abortion with a "46,XX" karyotype and 97 parents with aborted embryos. ...

Using genetic and cytogenetic markers, we assessed early development and X-chromosome inactivation (X-inactivation) in XX mouse androgenones produced by pronuclear transfer. Contrary to the current view, XX androgenones are capable of surviving to embryonic day 7.5, achieving basically random X-inactivation in all tissues including those derived from the trophectoderm and primitive endoderm tha...