Maternal zinc deficiency during pregnancy has been related to adverse pregnancy outcomes. Most studies in which pregnant women have been supplemented with zinc to examine effects on pregnancy outcome have been carried out in industrialized countries and the results have been inconclusive. This review discusses preliminary findings of eight randomized, controlled intervention trials performed re...

OBJECTIVE To update the available evidence about zinc use for treating diarrhea in children and to assess its effect on the malnourished population, a subgroup that has not been fully explored in previous analyses. METHODS A systematic review was performed of randomized clinical trials that assessed children up to 5 years old with acute diarrhea who received zinc supplementation. Controls rec...

BACKGROUND Micronutrient deficiencies remain common in preschool children in developing countries. Interventions focus on single micronutrients and often lack effectiveness. Weekly instead of daily supplementation may improve effectiveness. OBJECTIVE The efficacy of weekly and daily supplementation in reducing anemia prevalence and in improving the zinc, vitamin A, and growth status of 6-24-m...

Zinc ions highly concentrate in hippocampus and play a key role in modulating spatial learning and memory. At a time when dietary fortification and supplementation of zinc have increased the zinc consuming level especially in the youth, the toxicity of zinc overdose on brain function was underestimated. In the present study, weaning ICR mice were given water supplemented with 15 ppm Zn (low dos...

effect of levels of zinc supplementation on footpad lesions, reproductive and blood parameters of broiler breeders with 300 hens and 40 roosters of ross 308 strain with four treatments, five replicates and 15 hens and two roosters in each for 12 weeks was evaluated in a completely randomized design. dietary treatments were 80, 110, 140 and 170 mg zinc/kg diet. increasing supplemental zinc level...

UNLABELLED Child eating behaviors play an important role in nutrient intake, ultimately affecting child growth and later outcomes in adulthood. The study assessed the effects of iron-folic acid and zinc supplementation on child temperament and child eating behaviors in rural Nepal. Children (N = 569) aged 4-17 months in Sarlahi district, southern Nepal were randomized to receive daily supplemen...

Nuclear factor-kappaB (NF-kappaB) and AP-1 nuclear transcriptional factors regulate expression of multiple genes involved in tumor growth, metastasis and angiogenesis; however, the relative contribution of each factor to cancer initiation and progression has not been established. Prostate carcinogenesis involves transformation of normal zinc-accumulating epithelial cells to malignant cells that...

hyperglycemia and gestational diabetes mellitus are complications of pregnancy. both mothers and newborns are typically at increased risk for complications. this study sought to determine effect of zinc supplementation on serum glucose levels, insulin resistance, energy and macronutrients intakes in pregnant women with impaired glucose tolerance.in this clinical trial 44 pregnant women with imp...

the effect of different levels of zinc and copper organic supplements on performance, plasma copper plus zinc status, serum alkaline phosphatase (alp), ceruloplasmin (cp) activity as well as vitamin ¬a concentration was studied in 25 mehraban male lambs each of 5-6 months of age and 30/64±3/47kg of live weight. the following five dietary treatments were used: 1) control (base diet with no addit...

It has previously been established that zinc (Zn) supplementation increases bone dimensions and strength in growing rats. The present study aims at describing differences in the localization of loosely bound or free zinc ions, as revealed by autometallography (AMG), that might take place in the skeleton of growing rats following alimentary zinc depletion and supplementation. Male Wistar rats, 4...